Publications

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Pizzagalli Lab (LATN)

Publications in Press

Dan, R., Brown, A.R., Hutson, L., Belleau, E.L., Esfand, S.M., Ruberto, V., Johns, E., Null, K.E., Du, F., Pizzagalli, D.A. (in press). Brain encoding during perceived control as a prospective predictor of improvement in quality of life. Social Cognitive and Affective Neuroscience.

Dan, R., Pizzagalli, D.A. (in press). Brain-based graph-theoretical predictive modeling: A novel approach to prospectively map psychiatric symptoms. Neuropsychopharmacology.

Gigli, V.*, Castellano, P.*, Ghezzi, V., Ang, Y-S., Schettino, M., Pizzagalli, D.A., Ottaviani, C. (in press). Daily social isolation maps onto distinctive features of anhedonic behavior: A combined ecological and computational investigation. Biological Psychiatry: Global Open Science. [*Equal first authorship]

Gunn, M.P., Rose, G.M., Whitton, A.E., Pizzagalli, D.A., Gilbert, D.G. (in press). Smoking progression and nicotine-enhanced reward sensitivity predicted by resting-state functional connectivity in salience and executive control networks. Nicotine & Tobacco Research. 2024 Apr 16:ntae084. doi: 10.1093/ntr/ntae084. Online ahead of print.

Harnett, N.G., Fani, N., Carter, S., Sanchez, L.D., Rowland, G.E., Davie, W.M., Guzman, C., Lebois, L.A.M., Ely, T.D., van Rooij, S.J.H., Seligowski, A.V., Winters, S., Grasser, L.R., Musey, P.I., Seamon, M.J., House, S.L., Beaudoin, F.L., An, X., Zeng, D., Neylan, T.C., Clifford, G.D., Linnstaedt, S.D., Germine, L.T., Bollen, K.A., Rauch, S.L., Haran, J.P., Storrow, A.B., Lewandowski, C., Hendry, P.L., Sheikh, S., Jones, C.W., Punches, B.E., Swor, R.A., Hudak, L.A., Pascual, J.L., Harris, E., Chang, A.M., Pearson, C., Peak, D.A., Merchant, R.C., Domeier, R.M., Rathlev, N.K., Bruce, S.E., Miller, M.W., Pietzrak, R.H., Joorman, J., Barch, D.M., Pizzagalli, D.A., Harte, S.E., Elliott, J.M., Kessler, R.C., Koenen, K.C., McLean, S.A., Jovanovic, T., Stevens, J.S., Ressler, K.J. (in press). Structural inequities contribute to racial/ethnic differences in neurophysiological tone, but not threat reactivity, after trauma exposure. Molecular Psychiatry.

Hinojosa, C.A., van Rooij, S.J.H., Fani, N., Ellis, R.A., Harnett, N.G., Lebois, L.A.M., Ely, T.D., Jovanovic, T., Murty, V.P., House, S.L., Beaudoin, F., An, X., Neylan, T.C., Clifford, G.D., Linnstaedt, S.D., Germine, L.T., Rauch, S.L., Haran, J.P., Storrow, A.B., Lewandowski, C., Musey Jr., P.I., Hendry, P.L., Sheikh, S., Jones, C.W., Punches, B.E., Hudak, L.A., Pascual, J.L., Seamon, M.J., Harris, E., Pearson, C., Peak, D.A., Merchant, R.C., Domeier, R.M., Rathlev, N.K., O’Neil, B.J., Sergot, P., Bruce, S.E., Pizzagalli, D.A., Sheridan, J.F., Harte, S.E., Koenen, K.C., Kessler, R.C., McLean, S., Ressler, K.J., & Stevens, J.S. (in press). Reward neurocircuitry predicts longitudinal changes in traumatic stress-related alcohol use. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.

Hutson, L.M.*, Dan, R.*, Brown, A.R., Esfand, S.M., Ruberto, V.L., Johns. E., Null, K.E., Ohashi. K., Khan, A., Du, F., Teicher. M.H., Pizzagalli, D.A. (in press). Childhood sexual abuse and lifetime depressive symptoms: The importance of type and timing of childhood emotional maltreatment. Psychological Medicine [*Equal contribution]

Kim, N., Bloom, P.A., Rosellini, A.J., Webb, C.A., Pizzagalli, D.A., Auerbach, R.P. (in press). Probing neurophysiological processes related to self-referential processing to predict improvement for depressed adolescents receiving cognitive behavioral therapy. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.  

Kuhn, M.*, Steinberger, D.C.*, Bendezú, J.J., Ironside, M., Kang, M.S., Null, K.E., Brunner, D.L., Pizzagalli, D.A. (in press). Psychobiological stress response profiles in current and remitted depression: A person-centered, multisystem approach. Biological Psychiatry: Global Open Science. [*Equal contribution]

Liverant, G.I., Arditte Hall, K.A., Wieman, S.T., Pineles, S.L., Pizzagalli, D.A. (in press). Associations between insomnia and reward learning in clinical depression. Psychological Medicine.

Santos, J.L.C., Harnett, N.G., van Rooij, S.J.H, Ely, T.D., Jovanovic, T., Lebois, L.A.M., Beaudoin, F.L., An, X., Neylan, T.C., Linnstaedt, S.D., Germine, L.T., Bollen, K.A., Rauch, S.L., Haran, J.P., Storrow, A.B., Lewandowski, C., Musey, P.I. Jr, Hendry, P.L., Sheikh, S., Jones, C.W., Punches, B.E., Pascual, J.L., Seamon, M.J., Harris, E., Pearson, C., Peak, D.A., Merchant, R.C., Domeier, R.M., Rathlev, N.K., O’Neil, B.J., Sergot, P., Sanchez, L.D., Bruce, S.E., Pizzagalli, D.A., Harte, S.E., Ressler, K.J., Koenen, K.C., McLean, S.A., Stevens, J.S. (in press). Social buffering of PTSD: Longitudinal effects and neural mediators. Biological Psychiatry Cognitive Neuroscience and Neuroimaging. 2024 Nov 25;. [Epub ahead of print]

Sendi, M.S.E., Fu, Z., Harnett, N.G., van Rooij, S.J.H., Vergara, V., Pizzagalli, D.A., Daskalakis, N.P., House, S.L., Beaudoin, F.L., An, X., Neylan, T.C., Clifford, G.D., Jovanovic, T., Linnstaedt, S.D., Germine, L.T., Bollen, K.A., Rauch, S.L., Haran, J.P., Storrow, A.B., Lewandowski, C., Musey, P.I. Jr., Hendry, P.L., Sheikh, S., Jones, C.W., Punches, B.E., Swor, R.A., Gentile, N.T., Murty, V.P., Hudak, L.A., Pascual, J.L., Seamon, M.J., Harris, E., Chang, A.M., Pearson, C., Peak, D.A., Merchant, R.C., Domeier, R.M., Rathlev, N.K., O’Neil, B.J., Sergot, P., Sanchez, L.D., Bruce, S.E., Sheridan, J.F., Harte, S.E., Kessler, R.C., Koenen, K.C., McLean, S.A., Stevens, J.S., Calhoun, V.D., Ressler, K.J. (in press). Brain dynamics reflecting an intra-network brain state is associated with increased posttraumatic stress symptoms in the early aftermath of trauma. Nature Mental Health.

Turner, O., Punia, K., Pizzagalli, D.A., MacKillop, J., Balodis, I.M. (in press). Reward learning capacity in a community sample of individuals who use cannabis. Exp Clin Psychopharmacol. 2023 Dec 21. doi: 10.1037/pha0000701. Online ahead of print.

Voetterl, H.T.S., Sack, A.T., Olbrich, S., Stuiver, S., Rouwhorst, R., Prentice, A., Pizzagalli, D.A., van der Vinne, N., van Waarde, J.A., Brunovsky, M., van Oostrom, I., Reitsma, B., Fekkes, J., van Dijk, H., Arns, M. (in press). Utility of alpha peak frequency-based Brainmarker-I in antidepressant treatment stratification: Blinded out-of-sample validations for pharmacotherapy and brain stimulation. Nature Mental Health.

Webb, E.K., Stevens, J.S., Ely, T.D., Lebois, L.A.M., van Rooij, S.J.H., Bruce, S.E., House, S.L., Beaudoin, F.L., An, X., Neylan, T.C., Clifford, G.D., Linnstaedt, S.D., Germine, L.T., Bollen, K.A., Rauch, S.L., Haran, J.P., Storrow, A.B., Lewandowski, C., Musey, P.I., Hendry, P.H., Sheikh, S., Jones, C.W., Punches, B.E., Swor, R.A., Murty, V.P., Hudak, L.A., Pascual, J.L., Seamon, M.J., Datner, E.M., Pearson, C., Peak, D.A., Domeier, R.M., Rathlev, N.K., O’Neil, B.J., Sergot, P., Sanchez, L.D., Joormann, J., Pizzagalli, D.A., Harte, S.E., Kessler, R.C., Koenen, K.C., Ressler, K.J., McLean, S.A., Harnett, N.G. (in press). The role of individual and neighborhood resources on psychological trajectories and neural reactivity to reward following trauma. JAMA Psychiatry.

Whitton, A.E., Kumar, P., Treadway, M.T., Rutherford, A.V., Ironside, M.L., Foti, D., Fitzmaurice, G., Du, F., Pizzagalli, D.A. (in press). Distinct profiles of anhedonia and reward processing and their prospective associations with quality of life among individuals with mood disorders. Molecular Psychiatry.

Wong, S.A., Lebois, L.A.M., Ely, T.D., van Rooij, S.J.H., Bruce, S.E., Murty, V.P., Jovanovic, T., House, S.L., Beaudoin, F.L., An, X., Zeng, D., Neylan, T.C., Clifford, G.D., Linnstaedt, S.D., Germine, L.T., Bollen, K.A., Rauch, S.L., Haran, J.P., Storrow, A.B., Lewandowski, C., Musey, P.I., Hendry, P.L., Sheikh, S., Jones, C.W., Punches, B.E., Kurz, M.C., Swor, R.A., Hudak, L.A., Pascual, J.L., Seamon, M.J., Pearson, C., Peak, D.A., Merchant, R.C., Domeier, R.M., Rathlev, N.K., O’Neil, B.J., Sergot, P., Sanchez, L.D., Miller, M.W., Pietrzak, R.H., Joormann, J., Barch, D.M., Pizzagalli, D.A., Harte, S.E., Elliott, J.M., Kessler, R.C., Koenen, K.C., McLean, S.A., Ressler, K.J., Stevens, J.S., Harnett, N.G. (in press). Internal capsule microstructure mediates the relationship between childhood maltreatment and PTSD following adulthood trauma exposure. Molecular Psychiatry. 023 Mar 17. doi: 10.1038/s41380-023-02012-3. Online ahead of print.

Pizzagalli Lab (LATN)

2025 Publications

Cusin, C., Dillon, D.G., Belleau, E., Normandin, M.D., Petibon, Y., El-Fakri, G., Dhaynaut, M., Hooker, J., Kaptchuk, T., McKee, M., Hayden, E., Meyer, A., Jahan, A., Origlio, J., Ang, Y-S., Brunner, D., Kang, M., Long, Y., Fava, M.*, Pizzagalli, D.A.* (2025). Novel multi-modal methodology to investigate placebo response in Major Depressive Disorder. Journal of Affective Disorders, 368, 1-7. [*Equal senior authorship]. (PDF)

Kuhn, M.*, Steinberger, D.C.*, Bendezú, J.J., Ironside, M., Kang, M.S., Null, K.E., Brunner, D.L., Pizzagalli, D.A. (2025). Psychobiological stress response profiles in current and remitted depression: A person-centered, multisystem approach. Biological Psychiatry: Global Open Science, 5, 100400, https://doi.org/10.1016/j.bpsgos.2024.100400 [*Equal contribution]. (PDF)

Pizzagalli Lab (LATN)

2024 Publications

Dan, R., Whitton, A.E., Treadway, M.T., Rutherford, A.V., Kumar, P., Ironside, M.L., Kaiser, R.H., Ren, B., Pizzagalli, D.A. (2024). Brain-based graph-theoretical predictive modeling to map the trajectory of anhedonia, impulsivity, and hypomania from the human functional connectome. Neuropsychopharmacology, 49, 1162-1170. (PDF)

Dercon, Q., Mehrhof, S.Z., Sandhu, T.R., Hitchcock, C., Lawson, R.P., Pizzagalli, D.A., Dalgleish, T., Nord, C.L. (2024). A core component of psychological therapy causes adaptive changes in computational learning mechanisms. Psychological Medicine, 54, 327-337. (PDF)

Dillon, D.G., Belleau, E.L., Origlio, J., McKee, M., Jahan, A., Meyer, A., Souther, M.K., Brunner, D., Kuhn, M., Ang, Y-S., Cusin, C., Fava, M., Pizzagalli, D.A. (2024). Using drift diffusion and RL models to disentangle effects of depression on decision-making vs. learning in the probabilistic reward task. Computational Psychiatry, 8, 46-69. (PDF)

Dong, D., Pizzagalli, D.A., Bolton, T.A.W., Ironside, M., Zhang, X., Li, C., Sun, X., Xiong, G., Cheng, C., Wang, X., Yao, S.*, Belleau, E.L.* (2024). Sex-specific resting state brain network dynamics in patients with major depressive disorder. Neuropsychopharmacology, 49, 806–813. (PDF)

Duda, J.M.*, Moser, A.D.* Ironside, M., Null, K.E., Holsen, L.M., Zuo, C.S., Du, F., Esfand, S.M., Chen, X., Perlo, S., Richards, C.E., Lobien, R., Alexander, M., Misra, M., Goldstein, J.M.#, Pizzagalli, D.A.# (2024). Effects of GABA, sex, and stress on reward learning in current and remitted major depression. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 9, 606-615. [*Equal first authorship; #Equal senior authorship]. (PDF)

Ekhtiari, H., Sangchooli, A., Carmichael, O., Moeller, F.G., O’Donnell, P., Oquendo, M., Paulus, M.P., Pizzagalli, D.A., Ramey, T., Schacht, J., Zare-Bidoky, M., Childress, A.R., Brady, K. (2024). Neuroimaging biomarkers in addiction. Nature Mental Health, 2, 1498-1517. https://www.nature.com/articles/s44220-024-00334-x

Esfand, S.M., Null, K.E., Duda, J.M., de Leeuw, J., Pizzagalli, D.A. (2024). Lifetime history of major depressive disorder is associated with decreased reward learning: Evidence from a novel online version of the Probabilistic Reward Task. Journal of Affective Disorders, 350, 1007-1015. (PDF)

Floresco, S., Roberts., A., Robinson, E., Pizzagalli, D.A. (2024). Preclinical animal models and assays of neuropsychiatric disorders: Old problems and new vistas – Introduction to the Special Issue. Cognitive, Affective, & Behavioral Neuroscience, 24, 187-190. (PDF)

Ging-Jehli, N.R.*, Kuhn, M.*, Blank, J.M., Chanthrakumar, P., Steinberger, D.C., Yu, Z., Herrington, T.M., Dillon, D.G., Pizzagalli, D.A.**, Frank, M.J.** (2024). Cognitive signatures of depressive and anhedonic symptoms, and affective states, using computational modeling and neurocognitive testing. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 9, 726-736. [*Equal first authorship, **Equal senior authorship.] (PDF)

Gollan, J.K., Liverant, G., Jao, N.C., Lord, K.A., Whitton, A.E., Hogarth, L., Fox, E., Bauer, A.M., Quinn, M.H., Pizzagalli, D.A., Leone, F.T., Papandonatos, G.D., Schnoll, R.A., Hitsman, B. (2024). Depression severity moderates reward learning among smokers with current or past Major Depressive Disorder in a smoking cessation randomized clinical trial. Nicotine & Tobacco Research, 26, 639-644. (PDF)

Gunn, M.P., Rose, G.M., Whitton, A.E., Pizzagalli, D.A., Gilbert, D.G. (2024). Smoking progression and nicotine-enhanced reward sensitivity predicted by resting-state functional connectivity in salience and executive control networks. Nicotine & Tobacco Research, 26, 1305-1312. (PDF)

Gupta, T., Eckstrand, K.L., Lenniger, C.J., Haas, G.L., Silk, J.S., Ryan, N.D., Phillips, M.L., Flores Jr., L.E., Pizzagalli, D.A., Forbes, E.E. (2024). Anhedonia in adolescents at transdiagnostic familial risk for severe mental illness: Clustering by symptoms and mechanisms of associations with behavior. Journal of Affective Disorders, 347, 249-261. (PDF)

Hinojosa, C.A., Liew, A., An, X., Stevens, J.S., Basu, A., van Rooij, S.J.H., House, S.L., Beaudoin, F.L., Zeng, D. Neylan, T.C., Clifford, G.D., Jovanovic, T., Linnstaedt, S.D., Germine, L.T., Rauch, S.L., Haran, J.P., Storrow, A.B., Lewandowski, C., Musey, P.I, Hendry, P.L., Sheikh, S., Jones, C.W., Punches, B.E., Kurz, M.C., Swor, R.A., Hudak, L.A., Pascual, J.L., Seamon, M.J., Datner, E.M., Chang, A.M., Pearson, C., Peak, D.A., Merchant, R.C., Domeier, R.M., Rathlev, N.K., Sergot, P., Sanchez, L.D., Bruce, S.E., Miller, M.W., Pietrzak, R.H., Joormann, J., Pizzagalli, D.A., Sheridan, J.F., Harte, S.E., Elliott, J.M., Kessler, R.C., Koenen, K.C., McLean, S.A., Ressler, K.J., Fani, N. (2024). Associations of alcohol and cannabis use with change in posttraumatic stress disorder and depression symptoms over time in recently trauma-exposed individuals. Psychological Medicine, 54, 338-349. (PDF)

Hubbard, N.A., Bauer, C.C.C., Siless, V., Auerbach, R.P., Elam, J.S., Frosch, I.R., Henin, A., Hofmann, S.G., Hodge, M.R., Jones, R., Lenzini, P., Lo, N., Park, A.T., Pizzagalli, D.A., Vaz-DeSouza, F., Gabrieli, J.D.E., Whitfield-Gabrieli, S., Yendiki, A., Ghosh, S.S. (2024). The Human Connectome Project of adolescent anxiety and depression dataset. Scientific Data, 11, 837. doi: 10.1038/s41597-024-03629-x. (PDF)

Hyatt, C.S., Reddi, P.J., Sharpe, B.M., Michopoulos, V., van Rooij, S.J., House, S.L., Beaudoin, F.L., An, X., Stevens, J.S., Zeng, D., Neylan, T.C., Clifford, G.D., Linnstaedt, S.D., Germine, L.T., Bollen, K.A., Rauch, S.L., Haran, J.P., Lewandowski, C., Musey, Jr. P.I., Hendry, P.L., Sheikh, S., Jones, C.W., Punches, B.E., Kurz, M.C., Swor, R.A., Hudak, L.A., Pascual, J.L., Seamon, M.J., Harris, E., Pearson, C., Peak, D.A., Merchant, R.C., Domeier, R.M., Rathlev, N.K., Sergot, P., Sanchez, L.D., Bruce, S.E., Miller, M.W., Pietrzak, R.H., Joormann, J., Pizzagalli, D.A., Sheridan, J.F., Smoller, J.W., Harte, S.E., Elliott, J.M., McLean, S.A., Kessler, R.C., Ressler, K.J., Koenen, K.C., Maples-Keller, J.L. (2024). Longitudinal associations between five factor model and impulsive personality traits and PTSD symptoms: Findings from the AURORA study. The Journal of Research in Personality, 112, 104524. (PDF)

Ironside, M., Duda, J.M., Moser, A.D., Holsen, L.M., Zuo, C.S., Du, F., Perlo, S., Richards, C.E., Chen, X., Nickerson, L.D., Null, K.E., Esfand, S.M., Alexander, M.M., Crowley, D.J., Lauze, M., Misra, M., Goldstein, J.M.*, Pizzagalli, D.A.* (2024). Lower rostral anterior cingulate GABA+ and dysregulated cortisol stress response are associated with altered functional connectivity in young adults with lifetime depression: A multimodal imaging investigation of trait and state effects. American Journal of Psychiatry, 181, 639-650. [*Equal senior contribution] (PDF)

Jain, A.*, Schoeller F.*, Esfand, S., Duda, J., Null, K., Reggente, N., Pizzagalli, D.A., Maes, P. (2025). Aesthetic chills modulate reward learning in anhedonic depression. Journal of Affective Disorders, 370, 9-17. [*Equal contribution] (PDF)

Kangas, B.D., Ang, Y.-S., Short, A.K., Baram, T.Z., Pizzagalli, D.A. (2024). Computational modeling differentiates learning rate from reward sensitivity deficits produced by early life adversity in a rodent touchscreen Probabilistic Reward Task. Biological Psychiatry: Global Open Science, 6, November 2024, 100362. (PDF)

Kirshenbaum, J.S., Pagliaccio, D., Pizzagalli, D.A.*, Auerbach, R.P.* (2024). Neural sensitivity following stress predicts anhedonia symptoms: A 2-year multi-wave, longitudinal study. Translational Psychiatry. (2024) 14:106 ; https://doi.org/10.1038/s41398-024-02818-x [*Equal senior-authorship]. (PDF)

Linton, S.R.*, Lees, T.*, Iturra-Mena, A., Kangas, B.D., Nowicki, G., Lobien, R., Vitaliano, G., Bergman, J., Carlezon, W.A., Pizzagalli, D.A. (2014). Behavioral and neurophysiological signatures of cognitive control in humans and rats. International Journal of Neuropsychopharmacology, 27, November 2024, pyae050, https://doi.org/10.1093/ijnp/pyae050. [*Equal contributions] (PDF)

Min, A., Mazurka, R., Pizzagalli, D.A., Whitton, A.E., Milev, R.V., Bagby, R.M., Kennedy, S.H., Harkness, K.L. (2024). Stressful life events and reward processing in adults: Moderation by depression and anhedonia. Depression and Anxiety, vol. 2024, Article ID 8853631, https://doi.org/10.1155/2024/8853631. (PDF)

Null, K.E., Duda, J.M., Pizzagalli, D.A. (2024). Social support mediates the effects of childhood unpredictability on anhedonia: A retrospective investigation in an online adult community sample. Journal of Mood and Anxiety Disorders, 6 (2024) 100057. (PDF)

Olson, E.A., Ahmad, S., Granger, S.J., Ashraf, A., Pizzagalli, D.A., Rosso, I.M. (2024). Anhedonia and delay discounting: Differing patterns of brain-behavior relationships in healthy control participants versus individuals with posttraumatic stress disorder. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 9, 80-90. (PDF)

Pizzagalli, D.A. (2024). Toward actionable neural markers of depression risk? Trends in Neuroscience, 47, 851-852. (PDF)

Sacchet, M.D., Keshava, P. Walsh, S.W., Potash, R.M., Kullar, M., Li, M., Liu, H., Pizzagalli, D.A. (2024). Individualized functional brain system topologies and major depressive disorder: Relations among person-specific functional patch sizes and diagnosis, symptoms, and behavior. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 9, 616-625. (PDF)

Schoeller, F., Jain, A., Pizzagalli, D.A., Reggente, N. (2024). The neurobiology of aesthetic chills: How bodily sensations shape emotional experiences. Cognitive, Affective, and Behavioral Neuroscience, 24, 617-630. (PDF)

Stewart, J.G., Pizzagalli, D.A., Auerbach, R.P. (2024). Stress exposure in at-risk, depressed, and suicidal adolescents. Journal of Child Psychology and Psychiatry, 65, 942-958. (PDF)

Thai, M.*, Olson, E.A.*, Nickels, S., Dillon, D.G., Webb, C.A., Ren, B., Killgore, W.D.S., Rauch, S.L., Rosso, I.M.**, Pizzagalli, D.A.** (2024). Neural and behavioral markers of inhibitory control predict symptom improvement during internet-delivered cognitive behavioral therapy for depression. Translational Psychiatry 14, 303 (2024). https://doi.org/10.1038/s41398-024-03020-9 [*Co-first authorship, **Equal senior authorship]. (PDF)

Ulke, C., Kayser, J., Tenke, C.E., Mergl, R., Sander, C., Panier, L.Y.X., Alvarenga, J.E., Fava, M., McGrath, P.J., Deldin, P.J., McInnis, M.G., Trivedi, M.H., Weissman, M.M., Pizzagalli, D.A., Hegerl, U., Bruder, G.E. (2024). EEG measures of brain arousal in relation to symptom improvement in patients with major depressive disorder: Results from a randomized placebo-controlled clinical trial. Psychiatry Research, 342, 116165. (PDF)

van Rooij, S.J.H., Santos, J.L., Hinojosa, C.A., Ely, T.D., Harnett, N.G., Murty, V.P., Lebois, L.A.M., Jovanovic, T., House, S.L., Bruce, S.E., Beaudoin, F.L., An, X., Neylan, T.C., Clifford, G.D., Linnstaedt, S.D., Germine, L.T., Bollen, K.A., Rauch, S.L., Haran, J.P., Storrow, A.B., Lewandowski, C., Musey, P.I., Jr., Hendry, P.L., Sheikh, S., Jones, C.W., Punches, B.E., Swor, R.A., Pascual, J.L., Seamon, M.J., Harris, E., Pearson, C., Peak, D.A., Merchant, R.C., Domeier, R.M., Rathlev, N.K., O’Neil, B.J., Sanchez, L.D., Joormann, J., Pizzagalli, D.A., Sheridan, J.F., Harte, S.E., Kessler, R.C., Koenen, K.C., McLean, S.A., Ressler, K.J., Stevens, J.S. (2024). Defining the r factor for post-trauma resilience and its neural predictors. Nature Mental Health, 2, 690-693. (PDF)

Webb, E.K., Stevens, J.S., Ely, T.D., Lebois, L.A.M., van Rooij, S.J.H., Bruce, S.E., House, S.L., Beaudoin, F.L., An, X., Neylan, T.C., Clifford, G.D., Linnstaedt, S.D., Germine, L.T., Bollen, K.A., Rauch, S.L., Haran, J.P., Storrow, A.B., Lewandowski, C., Musey, P.I., Hendry, P.H., Sheikh, S., Jones, C.W., Punches, B.E., Swor, R.A., Murty, V.P., Hudak, L.A., Pascual, J.L., Seamon, M.J., Datner, E.M., Pearson, C., Peak, D.A., Domeier, R.M., Rathlev, N.K., O’Neil, B.J., Sergot, P., Sanchez, L.D., Joormann, J., Pizzagalli, D.A., Harte, S.E., Kessler, R.C., Koenen, K.C., Ressler, K.J., McLean, S.A., Harnett, N.G. (2024). Neighborhood resources associated with psychological trajectories and neural reactivity to reward after trauma. JAMA Psychiatry, 81, 1090-1100. (PDF)

Withey, S.L., Pizzagalli, D.A., Bergman, J. (2024). Translational in vivo assays in behavioral biology. Annual Review of Pharmacology and Toxicology, 64, 435-453. (PDF)

Zhukovsky, P.*, Ironside, M.*, Duda, J.M., Moser, A.D., Null1, K.E., Dhaynaut, M., Normandin, M., Guehl, N.J., El Fakhri, G., Alexander, M., Holsen, L.M., Misra, M., Narendran, R., Hoye, J., Morris, E., Esfand, S.M., Goldstein, J.M., Pizzagalli, D.A. (2024). Acute stress increases striatal connectivity with cortical regions enriched for μ- and κ-opioid receptors. Biological Psychiatry, 96, 717-726. [*Equal first authorship] (PDF)

Zhukovsky, P., Tio, E.S., Coughlan, G., Bennett, D.A., Wang, Y., Hohman, T.J., Pizzagalli, D.A., Mulsant, B.H., Voineskos, A.N.*, Felsky, D.* (2024). Genetic influences on brain and cognitive health and their interactions with cardiovascular conditions and depression. Nature Communications, 15, 5207 (2024). https://doi.org/10.1038/s41467-024-49430-7 [*Equal senior authorship]. (PDF)

Pizzagalli Lab (LATN)

2023 Publications

Ang, Y.S., Gelda, S.E., Pizzagalli, D.A. (2023). Cognitive effort-based decision making in major depressive disorder. Psychological Medicine. (PDF)

Beaudoin, F.L., An, X., Basu, A., Ji, Y., Liu, M., Kessler, R.C., Doughtery, R.F., Zeng. D., Bollen, K.A., House, S.L., Stevens, J.S., Neylan, T.C., Clifford, G.D., Jovanovic, T., Linnstaedt, S.D., Germine, L.T., Rauch, S.L., Haran, J.P., Storrow, A.B., Lewandowski, C., Musey, P.I., Hendry, P.L., Sheikh, S., Jones, C.W., Punches, B.E., Kurz, M.C., Swor, R.A., Murty, V.P., McGrath, M.E., Hudak, L.A., Pascual, J.L., Datner, E.M., Chang, A.M., Pearson, C., Peak, D.A., Merchant, R.C., Domeier, R.M., Rathlev, N.K., O’Neil, B.J., Sergot, P., Sanchez, L.D., Bruce, S.E., Baker, J.T., Joormann, J., Miller, M.W., Pietrzak, R.H., Barch, D.M., Pizzagalli, D.A., Sheridan, J.F., Smoller, J.W., Harte, S.E., Elliott, J.M., Koenen, K.C., Ressler, K.J., McLean, S.A. (2023). Use of serial smartphone-based assessments to characterize diverse neuropsychiatric symptom trajectories in a large trauma survivor cohort. Translational Psychiatry, 13, 4 (2023). https://doi.org/10.1038/s41398-022-02289-y. (PDF)

Baskaran, C., Kumar, P., Plessow, F., Nimmala, S., Ackerman, K.E., Eddy, K.T., Pizzagalli, D.A., Misra, M. (2023). Depressive and anxiety symptoms, and neural correlates of reward and punishment anticipation in female athletes with amenorrhea. Frontiers in Endocrinology. 14:976050. doi: 10.3389/fendo.2023.976050  (PDF)

Belleau, E.L., Kremens, R., Bolton, T.A.W., Bondy E., Pisoni, A., Auerbach, R.P., Pizzagalli, D.A. (2023). Default mode and frontoparietal network dynamics: Associations with familial risk for depression and stress sensitivity. Journal of Mood and Anxiety Disorders, 1, 100001, https://doi.org/10.1016/j.xjmad.2023.100001

Castellano, P., Gigli, V., Ghezzi, V., Ang, Y-S., Schettino, M., Pizzagalli, D.A., Ottaviani, C. (2023). Momentary gustative-olfactory sensitivity and tonic heart rate variability are independently associated with motivational behavior. International Journal of Psychophysiology, 186, 1-9. (PDF)

Darrow, S.M., Pizzagalli, D.A., Smoski, M., Mathew, S.J., Nurnberger, J., Lisanby, S.H., Iosifescu, D., Murrough, J.W., Yang, H., Weiner, R.D., Sanacora, G., Keefe, R.S.E., Song, A., Goodman, W., Whitton, A.E., Potter, W.Z., Krystal, A.D. (2023). Using Latent profile analyses to classify subjects with anhedonia based on reward-related measures obtained in the FAST-MAS study. Journal of Affective Disorder, 339, 584-592. (PDF)

Giles, M.A., Cooper, C.M., Jha, M.K., Chin Fatt, C.R., Pizzagalli, D.A., Mayes, T.L., Webb, C.A., Greer, T.L., Etkin, A., Trombello, J.M., Chase, H.W., Phillips, M.L., McInnis, M.G., Carmody, T., Adams, P., Parsey, R.V., McGrath, P.J., Weissman, M., Kurian, B.T., Fava, M., Trivedi, M.H. (2023). Reward behavior disengagement, a neuroeconomic model-based objective measure of reward pathology in depression: Findings from the EMBARC trial. Behavioral Sciences, 2023, 13, 619. (PDF)

Harnett, N.G., Dumornay, N.M., Delity, M., Sanchez, L.D., Mohiuddin, K., Musey, P.I. Jr., Seamon, M.J., McLean, S.A., Kessler, R.C., Koenen, K.C., Beaudoin, F.L., Lebois, L., van Rooij, S.J., Sampson, N.A., Michopoulos, V., Maples-Keller, J.L., Haran, J.P., Storrow, A.B., Lewandowski, C., Hendry, P.L., Sheikh, S., Jones, C.W., Punches, B.E., Kurz, M.C., Swor, R.A., McGrath, M.E., Hudak, L.A., Pascual, J.L., House, S.L., An, X., Stevens, J.S., Neylan, T.C., Linnstaedt, S.D., Germine, L.T., Datner, E.M., Chang, A.M., Pearson, C., Peak, D.A., Merchant, R.C., Domeier, R.M., Rathlev, N.K., O’Neil, B.J., Sergot, P., Bruce, S.E., Miller, M.W., Pietrzak, R.H., Joormann, J., Barch, D.M., Pizzagalli, D.A., Sheridan, J.F., Smoller, J.W., Luna, B., Harte, S.E., Elliott, J.M., Ressler, K.J. (2023). Prior differences in previous trauma exposure primarily drive the observed racial/ethnic differences in posttrauma depression and anxiety following a recent trauma. Psychological Medicine, 53, 2553-2562. (PDF)

Hubbard, N.A., Auerbach, R.P., Siless, V., Lo, N., Frosch, I.R., Clark, D.E., Jones, R., Kremens, R., Pinaire, M., Vaz De Souza, F., Ghosh, S.S., Henin, A., Hofmann, S.G., Pizzagalli, D.A., Rosso, I.M., Yendiki, A., Whitfield-Gabrieli, S., Gabrieli, J.D.E. (2023). Connectivity patterns evoked by fearful faces demonstrate reduced flexibility across a shared dimension of adolescent anxiety and depression. Clinical Psychological Science, 11, 3-22. (PDF)

Iturra‑Mena, A.M., Kangas, B.D., Luc, O.T., Potter, D., Pizzagalli, D.A. (2023). Electrophysiological signatures of reward learning in the rodent touchscreen-based Probabilistic Reward Task. Neuropsychopharmacology, 48, 700-709. (PDF)

Iturra-Mena, A.M., Kangas, B.D., Pizzagalli, D.A. Nociceptin receptor antagonism modulates electrophysiological markers of reward learning. The International Journal of Neuropsychopharmacology. (PDF)

Jones, W.C., An, X., Ji, Y., Liu, M., Zeng, D., House, S.L., Beaudoin, F.L., Stevens, JS, Neylan, T.C., Clifford, G.D., Jovanovic, J., Linnstaedt, S.D., Germine, G.T., Bollen, K.A., Rauch, S.L., Haran, J.P., Storrow, A.B., Lewandowski, C., Musey, Jr. P.I., Hendry, P.L., Sheikh, S., Punches, B.E., Lyons, M.S., Kurz, M.C., Swor, R.A., McGrath, M.E., Hudak, L.A., Pascual, J.L., Seamon, M.J., Datner, E.M., Harris, E., Chang, A.M., Pearson, C., Peak, D.A., Merchant, R.C., Domeier, R.M., Rathlev, N.K., O’Neil, B.J., Sergot, P., Sanchez, L.D., Bruce, S.E., Miller, M.W., Pietrzak, R.H., Joormann, J., Barch, D.M., Pizzagalli, D.A., Sheridan, J.F., Smoller, J.W., Harte, S.E., Elliott, J.M., Koenen, K.C., Ressler, K.J., Kessler, R.C., McLean, S.A. Derivation and validation of a brief ED-based prediction tool for posttraumatic stress after motor vehicle collision. Annals of Emergency Medicine , 81, 249-261. (PDF)

Kragel, P.A., Treadway, M.T., Admon, R., Pizzagalli, D.A., Hahn, E.C. (2023). A mesocorticolimbic signature of pleasure in the human brain. Nature Human Behaviour, 7, 1332-1343. https://www.nature.com/articles/s41562-023-01639-0 (PDF)

Lamontagne, S.J., Duda, J.M., Madarasmi, S., Rogers, V.A., Yu, E., Pizzagalli, D.A., Schroder, H.S. (2023). Limited impacts of biogenetic messaging on neural correlates of cognitive control and beliefs about depression. Cognitive, Affective, and Behavioral Neuroscience, 23, 383-399. (PDF)

Pagliaccio, D., Kumar, P., Kamath, R.A., Pizzagalli, D.A., Auerbach, R.P. (2023). Neural sensitivity to peer feedback and depression symptoms in adolescents: A 2-year multi-wave longitudinal study. Journal of Child Psychology and Psychiatry, 64, 254-264. (PDF)

Phillips, R. D., Walsh, E. C., Zürcher, N. R., Lalush, D., Kinard, J. L., Tseng, C.-E., Cernasov, P. M., Kan, D., Cummings, K. K., Kelley, L., Campbell, D. B., Dillon, D. G., Pizzagalli, D. A., Izquierdo-Garcia, D., Hooker, J. M., Smoski, M. J., & Dichter, G. S. (2023). Striatal dopamine binding in anhedonia: A simultaneous [11C]raclopride positron emission tomography and functional magnetic resonance imaging investigation. Psychiatry Research: Neuroimaging. Neuroimaging, 333, 111660. (PDF)

Ren, B., Balkind, E.G., Pastro, B., Israel, E.S.., Pizzagalli, D.A., Rahimi-Eichi, H., Baker, J.T., Webb, C.A. Predicting states of elevated negative affect in adolescents from smartphone sensors: A novel personalized machine learning approach. Psychological Medicine. (PDF)

Rief, W., Hofmann, S.G., Berg, M., Forbes, M.K., Pizzagalli, D.A., Zimmermann, J., Fried, E., Reed, G.M. (2023). Do we need a novel framework for classifying psychopathology? A discussion paper. Clinical Psychology in Europe, 5, article e11699, https://doi.org/10.32872/cpe.11699. (PDF)

Rolle, C.E., Pedersen, M.L., Johnson, N., Amemori, K., Ironside, M., Graybiel, A., Pizzagalli, D.A., Etkin, A. The role of the dorsal-lateral prefrontal cortex in reward sensitivity during Approach-Avoidance Conflict. Cerebral Cortex, 32, 1269-1285. (PDF)

Romer, A.L., Ren, B., Pizzagalli, D.A. (2023). Brain structure relations with psychopathology trajectories in the Adolescent Brain Cognitive Development Study®. Journal of the American Academy of Child and Adolescent Psychiatry, 62, 895-907. (PDF)

Rosmarin, D.H., Chowdhury, A., Pizzagalli, D.A., Sacchet, M. (2023). In God we trust: Effects of spirituality and religion on economic decision making. Personality and Individual Differences, 214, 112350. https://doi.org/10.1016/j.paid.2023.112350.

Rowland, G.E., Roeckner, A., Ely, T.D., Lebois, L.A.M., van Rooij, S.J.H., Bruce, S.E., Jovanovic, T., House, S.L., Beaudoin, F.L., An, X., Neylan, T.C., Clifford, G.D., Linnstaedt, S.D., Germine, L.T., Rauch, S.L., Haran, J.P., Storrow, A.B., Lewandowski, C., Musey, P.I., Jr, Hendry, P.L., Sheikh, S., Jones, C.W., Punches, B.E., Kurz, M.C., Gentile, N.T., Hudak, L.A., Pascual, J.L., Seamon, M.J., Harris, E., Pearson, C., Merchant, R.C., Domeier, R.M., Rathlev, N.K., Sergot, P., Sanchez, L.D., Miller, M.W., Pietrzak, R.H., Joormann, J., Pizzagalli, D.A., Sheridan,,J.F., Smoller, J.W., Harte, S.E., Elliott, J.M., Kessler, R.C., Koenen, K.C., McLean, S.A., Ressler, K.J., Stevens, J.S., Harnett N.G. (2023). Prior sexual trauma exposure impacts posttraumatic dysfunction and neural circuitry following a recent traumatic event in the AURORA study. Biological Psychiatry Global Open Science (2023). (PDF)

Straus, L.D., An, X., Ji, Y., Cakmak, A.S., Richards, A., Clifford, G.D., Liu, M., Zeng, D., House, S.L., Beaudoin, F.L., Stevens, J.S., Linnstaedt, S.D., Germine, L.T., Bollen, K.A., Rauch, S.L., Haran, J.P., Storrow, A.B., Lewandowski, C., Musey, P.I. Jr.., Hendry, P.L., Sheikh, S., Jones, C.W., Punches, B.E., Kurz, M.C., Swor, R.A., Hudak, L.A., Seamon, M.J., Datner, E.M., Chang, A.M., Pearson, C., Peak, D.A., Merchant, R.C., Domeier, R.M., Rathlev, N.K., O’Neil, B.J., Sergot, P., Sanchez, L.D., Bruce, S.E., Miller, M.W., Pietrzak, R.H., Joormann, J., Barch, D.M., Pizzagalli, D.A., Sheridan, J.F., Harte, S.E., Elliott, J.M., Kessler, R.C., Ressler, K.J., Koenen, K.C., McLean, S.A., Neylan, T.C. (2023). Utility of wrist-wearable data for assessing pain, sleep, and anxiety outcomes after traumatic stress exposure. JAMA Psychiatry, 80, 20-229. (PDF)

Wang, S., Kennedy, S.H., Salomons, T.V., Ceniti, A.K., McInerney, S.J., Bergmans, Y., Pizzagalli, D.A., Farb, N., Turecki, G., Schweizer, T.A., Churchill, N., Sinyor, M., Rizvi, S.J. (2023). Resting-state neural mechanisms of capability for suicide and their interaction with pain – A CAN-BIND-05 Study. Journal of Affective Disorders, 330, 139-147 (PDF)

Webb, C.A., Murray, L., Tierney, A.O., Forbes, E.E., Pizzagalli, D.A. (2023). Reward-related predictors of symptom change in behavioral activation therapy for anhedonic adolescents: A multimodal approach. Neuropsychopharmacology, 48, 623-632. (PDF)

Whitton, A.E., Kumar, P., Treadway, M.T., Rutherford, A.V., Ironside, M.L., Foti, D., Fitzmaurice, G., Du, F., Pizzagalli, D.A. (2023). Distinct profiles of anhedonia and reward processing and their prospective associations with quality of life among individuals with mood disorders. Molecular Psychiatry, 28, 5272-5281. (PDF)

Wong, S.A., Lebois, L.A.M., Ely, T.D., van Rooij, S.J.H., Bruce, S.E., Murty, V.P., Jovanovic, T., House, S.L., Beaudoin, F.L., An, X., Zeng, D., Neylan, T.C., Clifford, G.D., Linnstaedt, S.D., Germine, L.T., Bollen, K.A., Rauch, S.L., Haran, J.P., Storrow, A.B., Lewandowski, C., Musey, P.I., Hendry, P.L., Sheikh, S., Jones, C.W., Punches, B.E., Kurz, M.C., Swor, R.A., Hudak, L.A., Pascual, J.L., Seamon, M.J., Pearson, C., Peak, D.A., Merchant, R.C., Domeier, R.M., Rathlev, N.K., O’Neil, B.J., Sergot, P., Sanchez, L.D., Miller, M.W., Pietrzak, R.H., Joormann, J., Barch, D.M., Pizzagalli, D.A., Harte, S.E., Elliott, J.M., Kessler, R.C., Koenen, K.C., McLean, S.A., Ressler, K.J., Stevens, J.S., Harnett, N.G. (2023). Internal capsule microstructure mediates the relationship between childhood maltreatment and PTSD following adulthood trauma exposure. Molecular Psychiatry, 28, 5140-5149. (PDF)

Zhu, X., Lazarov, A., Dolan, S., Bar-Haim, Y., Dillon, D.G., Pizzagalli, D.A., Schneier, F. (2023). Resting state connectivity predictors of symptom change during gaze-contingent music reward therapy of social anxiety disorder. Psychological Medicine, 53(7), 3115-3123. (PDF)

Pizzagalli Lab (LATN)

2022 Publications

Ang, Y-S., Bruder, G.E., Keilp, J.G., Rutherford, A., Alschuler, D.M., Pechtel, P., Webb, C.A., Carmody, T., Fava, M., Cusin, C., McGrath, P.J., Weissman, M., Parsey, R., Oquendo, M.A., McInnis, M.G., Cooper, C.M., Deldin, P., Trivedi, M.H., Pizzagalli, D.A. (2022). Exploration of baseline and early changes in neurocognitive characteristics as predictors of treatment response to bupropion, sertraline, and placebo in the EMBARC clinical trial. Psychological Medicine, 52, 2441-2449. (PDF)

Ang Y-S, Cusin, C., Petibon, Y., Dillon, D.G., Breiger, M., Belleau, E.L., Normandin, M., Schroder, H., Boyden, S., Hayden, E., Levine, T., Jahan, A., Meyer, A.K., Kang, M-S., Brunner, D., Gelda, S.E., Hooker, J., El Fakhri. G., Fava, M., Pizzagalli, D.A. (2022). A multi-pronged investigation of option generation using depression, PET and modafinil. Brain, 145, 1854-1865. (PDF)

Auerbach, R.P., Pagliaccio, D., Hubbard, N.A., Frosch, I., Kremens, R., Cosby, E., Jones, R., Siless, V., Lo, N., Henin, A., Hofmann, S.G., Gabrieli, J.D.E., Yendiki, A., Whitfield-Gabrieli, S., Pizzagalli, D.A. (2022). Reward-related neural circuitry in depressed and anxious adolescents: A Human Connectome Project. Journal of the American Academy of Child and Adolescent Psychiatry, 61, 308-320. (PDF)

Belleau, E. L. (2022). Parsing Heterogeneity in Mood Disorders: The Challenges of Modeling Stable Mood Disorder–Related Functional Connectomes. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 7, 7-9. https://doi.org/10.1016/j.bpsc.2021.10.009. (PDF)

Belleau, E.L., Bolton, T.A.W., Kaiser, R.H., Clegg, R., Cardenas, E., Goer, F., Pechtel, P., Beltzer, M., Vitaliano, G., Olson, D.P., Teicher, M.H., Pizzagalli, D.A. (2022). Resting state brain network dynamics: Associations with childhood sexual abuse and major depressive disorder. NeuroImage: Clinical. 2022;36:103164. doi: 10.1016/j.nicl.2022.103164. (PDF)

Chang, R.S., Cerit, H., Hye, T., Durham, E.L., Aizley, H., Boukezzi, S., Haimovici, F., Goldstein, J.M., Dillon, D.G., Pizzagalli, D.A., Holsen, L.M. (in press). Stress-induced alterations in HPA-axis reactivity and mesolimbic reward activation in individuals with emotional eating. Appetite. ()

Citrome, L., Abi-Dargham, A., Bilder, R.M., Duffy, R.A., Dunlop, B.W., Harvey, P.D., Pizzagalli, D.A., Tamminga, C.A., McIntyre, R.S., Kane, J. (2022). Making sense of the matrix: A qualitative assessment and commentary on connecting psychiatric symptom scale items to the Research Domain Criteria (RDoC). Innovations in Clinical Neuroscience, 19, 26-32. (PDF)

Dillon, D.G., Lazarov, A., Dolan, S., Bar-Haim, Y., Pizzagalli, D.A., Schneier, F.R. (2022). Fast evidence accumulation in social anxiety disorder enhances decision making in a probabilistic reward task. Emotion, 22, 1-18. (PDF)

Dong, D., Belleau, E.L., Ironside, M., Zhong, X., Sun, Y., Xiong, G., Cheng, C., Li, C., Wang, X., Yao, S., Pizzagalli, D.A. (2022). Distinct stress-related medial prefrontal cortex activation in women with depression with and without childhood maltreatment. Depression and Anxiety, 39, 296-306. https://doi.org/10.1002/da.23243. (PDF)

Dong, D., Ironside, M., Belleau, E.L., Sun, X., Cheng, C., Xiong, G., Nickerson, L.D., Wang, X., Yao, S., Pizzagalli, D.A. (2022). Sex-specific neural responses to acute psychosocial stress in depression. Translational Psychiatry, 12. https://doi.org/10.1038/s41398-021-01768-y. (PDF)

Folorunso, O.O., Burns White, K., Alonso-Caraballo, Y., Nowicki, G.P., Olson, E.A., Pizzagalli, D.A., Carlezon, W.A., Jr, Ressler, K.J., Chartoff, E.H. Building an intentional and impactful summer research experience to increase diversity in mental health research. Neuropsychopharmacology, 47, 2189-2193.

Hanuka, S., Olson, E.A., Admon, R., Webb, C.A., Killgore, W.D.S., Rauch, S.L., Rosso, I.M.*, Pizzagalli, D.A.* (2022). Reduced anhedonia following internet-based cognitive behavioral therapy for depression is mediated by enhanced reward circuit activation. Psychological Medicine. 1-10. doi:10.1017/S0033291722001106 [*Equal senior contribution.]. (PDF)

Harnett, N.G., Finegold, K.E.,  Lebois, L.A.M., van Rooij, S.J.H., Ely, T.D., Murty, V.P., Jovanovic, T., Bruce, S.E., House, S.L., Beaudoin, F.L., An, X., Zeng, D., Neylan, T.C., Clifford, G.D., Linnstaedt, S.D., Germine, L.T., Bollen, K.E., Rauch, S.L., Haran, J.P., Storrow, A.B., Lewandowski, C., Musey, P.I., Hendry, P.L., Sheikh, S., Jones, C.W., Punches, B.E., Kurz, M.C., Swor, R.A., Hudak, L.A., Pascual, J.L., Seamon, M.J., Harris, E., Chang, A.M., Pearson, C., Peak, D.A., Domeier, R.M., Rathlev, N.K., O’Neil, B.J., Sergot, P., Sanchez, L.D., Miller, M.W., Pietrzak, R.H., Joormann, J., Barch, D.M., Pizzagalli, D.A., Sheridan. J.F., Harte, S.E., Elliott, J.M., Kessler, R.C., Koenen, K.C., McLean, S.A., Nickerson, L.D., Ressler, K.J., Stevens, J.S. (2022). Structural covariance of the ventral visual stream predicts posttraumatic intrusion and nightmare symptoms: a multivariate data fusion analysis. Translational Psychiatry. 022 Aug 8;12(1):321. doi: 10.1038/s41398-022-02085-8. (PDF)

Joormann, J., McLean, S.A., Beaudoin, F.L., An, X., Stevens, J.S., Zeng, D., Neylan, T.C., Clifford, G., Linnstaedt, S.D., Germine, L.T., Rauch, S., Musey, P.I., Hendry, P.L., Sheikh, S., Jones, C.W., Punches, B.E., Fermann, G., Hudak, L.A., Mohiuddin, K., Murty, V., McGrath, M.E., Haran, J.P., Pascual, J., Seamon, M., Peak, D.A., Pearson, C., Domeier, R.M., Sergot, P., Merchant, R., Sanchez, L.D., Rathlev, N.K., Peacock, W.F., Bruce, S.E., Barch, D., Pizzagalli, D.A., Luna, B., Harte, S.E., Hwang, I., Lee, S., Sampson, N., Koenen, K.C., Ressler, K., Kessler, R.C. (2022). Socio-demographic and trauma-related predictors of depression within eight weeks of motor vehicle collision in the AURORA study. Psychological Medicine, 52, 1934-1947. (PDF)

Kaiser, R.H., Chase, H.W., Phillips, M.L., Deckersbach, T., Parsey, R., Fava, M., McGrath, P., Weissman, M., Oquendo, M.A., McInnis, M.G., Carmody, T., Cooper, C.M., Trivedi, M.H., Pizzagalli, D.A. (2022). Dynamic resting-state network biomarkers of antidepressant treatment response. Biological Psychiatry, 92, 533-542. (PDF)

Kangas, B.D., Der-Avakian, A., Pizzagalli, D.A. (2022). Probabilistic reinforcement learning and anhedonia. Current Topics in Behavioral Neurosciences, 58, 355-377. (PDF)

Kangas, B.D., Short, A.K., Luc, O.T., Stern, H.S., Baram, T.Z., Pizzagalli, D.A. (2022). A cross-species assay demonstrates that reward responsiveness is enduringly impacted by adverse, unpredictable early-life experiences. Neuropsychopharmacology, 47, 767-775. (PDF)

Lebois, L.A.M., Harnett, N.G., van Rooij, S.J.H., Ely, T.D., Jovanovic, T., Bruce, S.E., House, S.L., Ravichandran, C., Dumornay, N.M., Finegold, K.E., Hill, S.B., Merker, J.B., Phillips, K.A., Beaudoin, F.L., An, X., Neylan, T.C., Clifford, G.D., Linnstaedt, S.D., Germine, L.T., Rauch, S.L., Haran, J.P., Storrow, A.B., Lewandowski, C., Musey, P.I., Jr, Hendry, P.L., Sheikh, S., Jones, C.W., Punches, B.E., Swor, R.A., McGrath, M.E., Hudak, L.A., Pascual, J.L., Seamon, M.J., Datner, E.M., Chang, A.M., Pearson, C., Domeier, R.M., Rathlev, N.K., O’Neil, B.J., Sergot, P., Sanchez, L.D., Miller, M.W., Pietrzak, R.H., Joormann, J., Barch, D.M., Pizzagalli, D.A., Sheridan, J.F., Smoller, J.W, Luna, B., Harte, S.E., Elliott, J.M., Kessler, R.C., Koenen, K.C., McLean, S.A., Stevens, J.S., Ressler, K.J. (2022). Persistent dissociation and its neural correlates in predicting outcomes after trauma exposure. American Journal of Psychiatry, 179, 661-672. (PDF)

Linton, S.R., Murphy, M., Schroder, H.S., Breiger, M., Iturra-Mena, A.N., Kangas, B.D., Bergman, J., Carlezon, W.A., Jr, Risbrough, V.B., Barnes, S.A., Der-Avakian, A., Pizzagalli, D.A. (2022). Effects of modafinil on electroencephalographic microstates in healthy adults. Psychopharmacology. 239, 2573-2584. (PDF)

Murray, L., Israel, E.S., Balkind, E.G., Pastro, B., Lovell-Smith, N., Lukas, S.E., Forbes, E.E., Pizzagalli, D.A., Webb, C.A. (2022). Multimodal assessment of reward functioning in adolescent anhedonia. Psychological Medicine. 1-10. doi:10.1017/S0033291722001222. (PDF)

Pechtel, P., Belleau, E.L., Kaiser, R.H., Whitton, A.E., Beltzer, M., Clegg, R., Goer, F., Vitaliano, G., Teicher, M.H., Pizzagalli, D.A. (2022). Stress and reward: A multimodal assessment of childhood sexual abuse. Neurobiology of Stress, 21, 100498. (PDF)

Pechtel, P., Harris, J., Karl, A., Clunies-Ross, C., Bower, S., Moberly, N.J., Pizzagalli, D.A., Watkins, E.R. (2022). Emerging ecophenotype: reward anticipation is linked to high-risk behaviours after sexual abuse. Social Cognitive and Affective Neuroscience, 17, 1035-1043. (PDF)

Piccolo, M., Belleau, E.L., Holsen, L.M., Trivedi, M.H., Parsey, R.V., McGrath, P.J., Weissman, M.M., Pizzagalli, D.A., Javaras, K.N. (2022). Alterations in resting state functional activity and connectivity for major depressive disorder appetite and weight disturbance phenotypes. Psychological Medicine. 1-11. doi:10.1017/S0033291722001398. (PDF)

Pizzagalli, D.A. (2022). Toward a better understanding of the mechanisms and pathophysiology of anhedonia: Are we ready for translation? American Journal of Psychiatry, 179, 458-469. (PDF)

Pizzagalli, D.A., Roberts, A.C. (2022). Prefrontal cortex and depression. Neuropsychopharmacology Review, 47, 225-246. (PDF)

Punches, B.E., Stolz, U.,  Freiermuth, C.E., Ancona, R.M., McLean, S.A., House, S.L., Beaudoin, F.L., An, X., Stevens, J.S., Zeng, D., Neylan, T.C., Clifford, G.D., Jovanovic, T., Linnstaedt, S.D., Germine, L.T., Bollen, K.A., Guffanti, G., Rauch, S.L., Haran, J.P., Storrow, A.B., Lewandowski, C., Musey, P.I., Jr., Hendry, P.L., Sheikh, S., Jones, C.W., Kurz, M.C., Swor, R.A., Gentile, N.T., Murty, V.P., McGrath, M.E., Hudak, L.A., Pascual, J.L., Seamon, M.J., Datner, E.M., Chang, A.M., Pearson, C., Peak, D.A., Merchant, R.C., Domeier, R.M., Rathlev, N.K., O’Neil, B.J., Sergot, P., Sanchez, L.D., Bruce, S.E., Miller, M.W., Pietrzak, R.H., Joormann, J., Barch, D.M., Pizzagalli, D.A.,  Sheridan, J.F., Smoller, J.W., Pace, T.W.W., Luna, B., Binder, E., Harte, S.E., Elliott, J.M., Kessler, R.C., Ressler, K.J., Koenen, K.C., Lyons, M.S. (2022). Predicting at-risk opioid use three months after ed visit for trauma: Results from the AURORA study. PLoS One. 2022 Sep 23;17(9):e0273378. doi: 10.1371/journal.pone.0273378. (PDF)

Rolle, C.E., Pedersen, M.L., Johnson, N., Amemori, K.I., Ironside, M., Graybiel, A.M., Pizzagalli, D.A., Etkin, A. (2022). The role of the dorsal-lateral prefrontal cortex in reward sensitivity during Approach-Avoidance Conflict. Cerebral Cortex, 32, 1269-1285. (PDF)

Romer, A.L., Pizzagalli, D.A. (2022). Associations between brain structural alterations, executive dysfunction, and general psychopathology in a healthy and cross-diagnostic adult patient sample. Biological Psychiatry: Global Open Science, 2, 17-27. (PDF)

Schroder. H.S., Iturra-Mena, A.M., Breiger. M., Linton, S.R., Robble, M.A., Kangas, B., Bergman, J., Nickels, S., Vitaliano, G., Der-Avakian, A., Barnes, S.A., Carlezon, W.A. Jr, Pizzagalli, D.A. (2022). Error-related alpha suppression: Scalp topography and (lack of) modulation by modafinil. Journal of Cognitive Neuroscience, 34, 864-876. (PDF)

Sezer, I., Pizzagalli, D.A., Sacchet, M.D. (2022). Resting-state fMRI functional connectivity and mindfulness in clinical and non-clinical contexts: a review and synthesis. Neuroscience and Biobehavioral Reviews, 135, 104583. (PDF)

Short, N.A., van Rooij, S.J.H., Murty, V.P., Stevens, J.S., An, X., Ji, Y., McLean, S.A., House, S.L., Beaudoin, F.L., Zeng, D., Neylan, T.C., Clifford, G.D., Linnstaedt, S.D., Germine, L.T., Bollen, K.A., Rauch, S.L., Haran, J.P., Lewandowski, C., Musey, P.I., Hendry, P.L., Sheikh, S., Jones, C.W., Punches, B.E., Swor, R.A., McGrath, M.E., Hudak, L.A., Pascual, J.L., Seamon, M.J., Datner, E.M., Pearson, C., Peak, D.A., Merchant, R.C., Domeier, R.M., Rathlev, N.K., O’Neil, B.J., Sergot, P., Sanchez, L.D., Bruce, S.E., Pietrzak, R.H., Joormann, J., Barch, D.M., Pizzagalli, D.A., Sheridan, J.F., Smoller, J.W., Harte, S.E., Elliott, J.M., Kessler, R.C., Koenen, K.C., Jovanovic, T. (2022). Anxiety sensitivity as a transdiagnostic risk factor for trajectories of adverse posttraumatic neuropsychiatric sequelae in the AURORA study. Journal of Psychiatric Research, 156, 45-54. (PDF)

Sperl, M.F.J., Panitz, C., Rosso, I.M., Dillon, D.G., Kumar, P., Hermann, A., Whitton, A.E., Hermann, C., Pizzagalli, D.A., Mueller, E.M. (2022). Alpha-2 adrenoreceptor antagonist yohimbine potentiates consolidation of conditioned fear. The International Journal of Neuropsychopharmacology, 25, 759-773. (PDF)

Tanriverdi, B., Gregory, D.F., Olino, T.M., Ely, T.D., Harnett, N.G., van Rooij. S.J.H., Lebois, L.A.M.,  Seligowski, A.V.,  Jovanovic, T., Ressler, K.J.,  House, S.L., Beaudoin, F.L.,  An, X.,  Neylan, T.C.,  Clifford, G.D.,  Linnstaedt, S.D.,  Germine, L.T.,  Bollen, K.A.,  Rauch, S.L., Haran, J.P.,  Storrow, A.B., Lewandowski, C., Musey, P.I.,  Hendry, P.L.,  Sheikh, S.,  Jones, C.W.,  Punches, B.E., Kurz, M.C.,  McGrath, M.E.,  Hudak, L.A., Pascual, J.L.,  Seamon, M.J., Datner, E.M.,  Pearson, C.,  Domeier, R.M.,  Rathlev, N.K., O’Neil, B.J.,  Sanchez, L.D.,  Bruce, S.E.,  Miller, M.W.,  Pietrzak, R.H.,  Joormann, J.,  Barch, D.M.,  Pizzagalli, D.A., Sheridan, J.F.,  Smoller, J.W., Harte, S.E.,  Elliott, J.M.,  McLean, S.A.,  Kessler, R.C., Koenen, K.C.,  Stevens, J.S.,  Murty, V.P. (2022). Hippocampal threat reactivity interacts with physiological arousal to predict PTSD symptoms. Journal of Neuroscience, 42, 6593-6604. (PDF)

Pizzagalli Lab (LATN)

2021 Publications

Ang, Y-S., Pizzagalli, D.A. (2021). Predictors of treatment outcome in adolescent depression. Current Treatment Options in Psychiatry, 8, 18-28. (PDF)

Bakusic, J., Vrieze, E., Ghosh, M., Pizzagalli, D.A., Bekaert, B., Claes, S., Godderis, L. (2021). Interplay of Val66Met and BDNF methylation: effect on reward learning and cognitive performance in major depression. Clinical Epigenetics, 13:149. doi: 10.1186/s13148-021-01136-z. (PDF)

Beaudoin, F.L., Kessler, R.C., Hwang, I., Lee, S., Sampson, N.A., An, X., Ressler, K.J., Koenen, K.C., McLean, S.A., the AURORA Study Group (2021).  Pain After a motor vehicle crash: The role of socio‐demographics, crash characteristics and peri‐traumatic stress symptoms. European Journal of Pain, 25, 1119-1136. [Dr. Pizzagalli listed 48th of 59 authors] (PDF)

Belleau, E.L., Kremens, R., Ang, Y-S, Pisoni, A., Bondy, E., Durham, K., Auerbach, R.P.*, Pizzagalli, D.A.* (2021). Reward functioning abnormalities in adolescents at high familial risk for depressive disorders. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 6, 270-279. [Equal senior contribution] (PDF)

Benschop, L., Poppa, T., Medani, T., Shahabi, H., Baeken, C., Leahy, R.M., Pizzagalli, D.A.*, Vanderhasselt, M-A*. (2021). Electrophysiological scarring in remitted depressed patients: Elevated EEG functional connectivity between the posterior cingulate cortex and the subgenual prefrontal cortex as a neural marker for rumination. Journal of Affective Disorders, 281, 493-450. [*Equal senior contributions.] (PDF)

Cakmak, A.S., Perez Alday, E.A., Da Poian, G., Bahrami Rad, A., Metzler, T.J., Neylan, T.C., House, S.L., Beaudoin, F.L., An, X, Stevens, J., Zeng, D., Linnstaedt, S.D., Jovanovic, T., Germine, L.T., Bollen, K.A., Rauch, S.L., Lewandowski, C., Hendry, P.L., Sheikh, S., Storrow, A.B., Musey, P.I., Haran, J.P., Jones, C.W., Punches, B.E., Swor, R.A., Gentile, N.T., Mcgrath, M.E., Seamon, M.J., Mohiuddin, K., Chang, A.M., Pearson, C., Domeier, R.M., Bruce, S.E., O’Neil, B.J., Rathlev, N.K., Sanchez, L.D., Pietrzak, R.H., Joormann, J., Barch, D.M., Pizzagalli, D., Harte, S.E., Elliott, J.M., Koenen, K.C., Ressler, K.J., Kessler, R., Li, Q., Mclean, S.A., Clifford, G.D. (2011). Classification and prediction of post-trauma outcomes related to PTSD using circadian rhythm changes measured via wrist-worn research watch in a large longitudinal cohort. IEEE Journal of Biomedical and Health Informatics, 25, 2866-2876. (PDF)

Cooper, J. A., Nuutinen, M.R., Lawlor, V.M.,  DeVries, B.A.M., Barrick, E.M., Hossein, S.,  Cole, D.C.,  Leonard, C.V., Hahn, E.C., Teer, A.P., Shields, G.S., Slavich, G.M., Ongur, D., Jensen, J.E.,  Du, F., Pizzagalli, D.A., Treadway, M.T. (2021). Reduced adaptation of glutamatergic stress response is associated with pessimistic expectations in depression. Nature Communications, 12, 3166 (2021). https://doi.org/10.1038/s41467-021-23284-9 (PDF)

Costi, S., Morris, L.S., Collins, A., Fernandez, N.F., Patel, M., Xie, H., Kim-Schulze, S., Stern, E.R., Collins, K.A., Cathomas, F., Parides, M.K., Whitton, A.E., Pizzagalli, D.A., Merad, M., Russo, S.J., Murrough, J.W. (2021). Peripheral immune cell reactivity and neural response to reward in patients with depression and anhedonia. Translational Psychiatry. 2021 Nov 5;11(1):565. (PDF) Costi, S., Morris, L.S., Kirkwood, K.A., Hoch, M., Corniquel, M., Vo-Le, B., Iqbal, T., Chadha, N., Pizzagalli, D.A., Whitton, A., Bevilacqua, L., Jha, M.K., Ursu, S., Swann, A.C., Collins, K.A., Salas, R., Bagiella, E., Parides, M.K., Stern, E.R., Iosifescu, D.V., Han, M.-H., Mathew, S.J., Murrough, J.W. (2021). Impact of the KCNQ2/3 channel opener ezogabine on reward circuit activity and clinical symptoms in depression: Results from a randomized controlled trial. American Journal of Psychiatry, 178, 437-446. (PDF)

Cunningham, S., Mazurka, R., Wynne-Edwards, K.E., Milev, R.V., Pizzagalli, D.A., Kennedy, S., Harkness, K.L. (2021). Cortisol reactivity to stress predicts behavioral responsivity to reward: Moderation by sex, depression, and anhedonia. Journal of Affective Disorders, 293, 1-8. (PDF)

Duda, J.M.*, Moser1, A.D.*, Zuo, C.S., Du, F., Chen, X., Perlo, S., Richards, C.E., Nascimento, N., Ironside, M., Crowley, D.J., Holsen, L.M., Misra, M., Hudson, J.I., Goldstein, J.M.#, Pizzagalli, D.A.# (2021). Repeatability PDF)

Finan, P.H., Letzen, J., Epstein, D.H., Mun, C.J., Stull, S., Kowalczyk, W.J., Agage, D., Phillips, K.A., Pizzagalli, D.A., Preston, K.L. (2021). Reward responsiveness in patients with opioid use disorder on opioid agonist treatment: Role of comorbid chronic pain. Pain Medicine, 22, 2019-2027. (PDF)

Germine, L.T., Passell, E., Scheuer, L., Martini, P., Hwang, I., Lee, S., Sampson, N., Barch, D.M., Kessler, R.C., Joormann, J., House, S.L., Beaudoin, F.L., An, X., Stevens, J.S., Zeng, D., Linnstaedt, S.D., Jovanovic, T., Clifford, G.D., Neylan, T.C., Bollen, K.A., Guffanti, G., Rauch, S.L., Lewandowski, C., Hendry, P.L., Sheikh, S., Storrow, A.B., Musey, Jr. P.I., Haran, J.P., Jones, C.W., Punches, B.E., Lyons, M.S., Kurz, M.C., Swor, R.A., Gentile, N.T., McGrath, M.E., Hudak, L.A., Pascual, J.L., Seamon, M.J., Mohiuddin, K., Chang, A.M., Pearson, C., Peak, D.A., Domeier, R.M., Merchant, R.C., Bruce, S.E., O’Neil, B.J., Rathlev, N.K., Sanchez, L.D., Pietrzak, R.H., Pizzagalli, D.A., Sheridan, J.F., Pace, T.W.W, Luna, B., Harte, S.E., Daly, M., Elliott, J.M., Koenen, K.C., Ressler, K.J., McLean, S.A. (2021). Neurocognition after motor vehicle collision and adverse post-traumatic neuropsychiatric sequelae within 8 weeks: Initial findings from the AURORA study. Journal of Affective Disorders, 298, 57-67. (PDF)

Harnett, N.G., van Rooij, S.J.H., Ely, T.D., Lebois, L.A.M., Murty, V.P., Jovanovic, T., Hill, S.B.,  Dumornay, N.M., Merker, J.B., Bruce, S.E., House, S.L., Beaudoin, F.L., An, X., Zeng, D., Neylan, T.C., Clifford, G.D., Linnstaedt, S.D., Germine, L.T., Bollen, K.A., Rauch, S.L., Lewandowski, C., Hendry, P.L., Sheikh, S., Storrow, A.B., Musey, P.I., Jr.19, Haran, J.P., Jones, C.W., Punches, B.E., Swor, R.A., McGrath, M.E., Pascual, J.L., Seamon, M.J., Mohiuddin, K., Chang, A.M., Pearson, C., Peak, D.A., Domeier, R.M., Rathlev, N.K., Sanchez, L.D., Pietrzak, R.H., Joormann, J., Barch, D.M., Pizzagalli, D.A., Sheridan, J.F., Harte, S.E., Elliot, J.M., Kessler, R.C., Koenen, K.C., Mclean, S., Ressler, K.J., Stevens, J.S. (2021). Prognostic neuroimaging biomarkers of trauma-related psychopathology: Resting state fMRI shortly after trauma predicts future PTSD and depression symptoms in the A>URORA study. Neuropsychopharmacology, 46, 1263-1271. (PDF)

Ironside, M., Moser, A.D., Holsen, L.M., Zuo, C.S., Du, F., Perlo, S, Richards, C.E., Duda, J.M., Chen, X., Nickerson, L.D., Null, K.E., Nascimento, N., Crowley, D.J., Misra, M., Goldstein, J.M.*, Pizzagalli, D.A.* (2021) Reductions in rostral anterior cingulate GABA are associated with stress circuitry in females with major depression: A multimodal imaging investigation. Neuropsychopharmacology, 46, 2188-2196. [*Equal senior contribution.] (PDF)

Joormann, J., Ziobrowski, H.N., King, A., Gildea, S.M., Lee, S., Sampson, N.A, House, S.L., Beaudoin, F.L., An, X., Stevens, J.S., Zeng, D., Neylan, T.C., Clifford, G.D., Linnstaedt, S.D., Germine, L.T., Bollen, K.E., Rauch, S.L., Haran, J.P., Storrow, A.B., Musey, P.I., Jr., Hendry, P.L., Sheikh, S., Jones, C.W.,  Punches, B.E., McGrath, M.E., Hudak, L.A., Pascual, J.L., Seamon, M.J., Chang, A.M., Pearson, C., Peak, D.A., Domeier, R.M., Rathlev, N.K., O’Neil, B.J., Sanchez, L.D., Bruce, S.E., Miller, M.W., Pietrzak, R.H., Barch, D.M., Pizzagalli, D.A., Harte, S.E.,  Elliott, J.M., Koenen, K.C., McLean, S.A., Kessler, R.C. (2022). Prior histories of posttraumatic stress disorder and major depression and their onset and course in the three months after a motor vehicle collision in the AURORA study. Depression and Anxiety, 39, 56-70. (PDF)

Ji, X., Zhao, J., Li, H., Pizzagalli, D.A., Law, S., Lin. P., Fan, L., Zhang. P., Fang, S., Wang, X., Yao, S., Wang, X. (2021). From motivation, decision-making to action: An fMRI study on suicidal behavior in patients with major depressive disorder. Journal of Psychiatric Research, 139, 14-24. (PDF)

Kangas, B.D., Iturra-Mena, A.M., Robble, M.A., Luc, O.T., Potter, D., Nickels, S., Bergman, J., Carlezon, W.A., Jr., Pizzagalli, D.A. (2021). Concurrent electrophysiological recording and cognitive testing in a rodent touchscreen environment. Scientific Reports. 2021 Jun 3;11(1):11665. doi: 10.1038/s41598-021-91091-9. (PDF)

Kessler, R.C., Ressler, K.J., House, S.L., Beaudoin, F.L., An, X., Stevens, J.S., Zeng, D., Neylan, T.C., Linnstaedt, S.D., Germine, L.T., Musey Jr., P.I., Hendry, P.L., Sheikh, S., Storrow, A.B., Jones, C.W., Punches, B.E., Datner, E.M., Mohiuddin, K., Gentile, N.T., McGrath, M.E., van Rooij, S.J., Hudak, L.A., Haran, J.P., Peak, D.A., Domeier, R.M., Pearson, C., Sanchez, L.D., Rathlev, N.K., Peacock, W.F., Bruce, S.E., Miller, M.W., Joormann, J., Barch, D.M., Pizzagalli, D.A., Sheridan, J.F., Smoller, J.W., Pace, T.W.W., Harte, S.E., Elliott, J.M., Harnett, N.G., Lebois, L.A.M., Hwang, I., Sampson, N.A., Koenen, K.C., McLean, S.A. (2021). Socio-demographic and trauma-related predictors of PTSD within 8 weeks of a motor vehicle collision in the AURORA study. Molecular Psychiatry, 26, 3108-3121. (PDF)

Lamontagne, S.J., Pizzagalli, D.A., Olmstead, M.C. (2021). Does inflammation link stress to poor COVID-19 outcome? Stress and Health, 37, 401-414. (PDF)

Lamontagne, S.J., Winters, M.F., Pizzagalli, D.A., Olmstead, M.C. (2021). Post-acute sequelae of COVID-19: Evidence of mood & cognitive impairment. Brain, Behavior, & Immunity – Health, 17, 100347. (PDF)

Lazarov, A., Basel, D., Dolan, S., Dillon, D.G., Pizzagalli, D.A., Schneier, F.R. (2021). Increased attention allocation to socially threatening faces in social anxiety disorder: A replication study. Journal of Affective Disorders, 290, 169-177. (PDF)

Lee, Y.J., Guell, X., Hubbard, N.A., Siless, V., Frosch. I.R., Goncalves, M., Lo, N., Nair, Auerbach, R.P., Pizzagalli, D.A., Yendiki, A., Gabrieli, J.D.E., Whitfield-Gabrieli, S., Anteraper, S.A. (2021). Functional alterations in cerebellar functional connectivity in anxiety disorders. Cerebellum, 20, 392-401. (PDF)

Luc, O.T., Pizzagalli, D.A., Kangas, B.D. (2022). Toward a quantification of anhedonia: Unified matching law and signal detection for clinical assessment and drug development. Perspectives on Behavior Science, 44, 517-540. (PDF)

Maffei, C., Lee, C., Planich, M., Ramprasad, M., Ravi, N., Trainor, D., Urban, Z., Kim, M., Jones, R.J., Henin, A., Hofmann, S.G., Pizzagalli, D.A., Auerbach, R.P., Gabrieli, J.D.E., Whitfield-Gabrieli, S., Greve, D.N., Haber, S.N., Yendiki, A. (2021). Using diffusion MRI data acquired with ultra-high gradient strength to improve tractography in routine-quality data. NeuroImage, 245, 118706. (PDF)

Murphy, M, Whitton, A.E., Deccy, S., Ironside, M.I., Rutherford, A., Beltzer., M., Sacchet, M., Pizzagalli, D.A. (2020). Abnormalities in electroencephalographic microstates are state and trait markers of major depressive disorder. Neuropsychopharmacology, 45, 2030-2037. (PDF)

Neylan, T.C., Kessler, R.C., Ressler, K.J., Clifford, G., Beaudoin, F.L., An, X., Stevens, J.S., Zeng, D., Linnstaedt, S.D., Germine, L.T., Sheikh, S., Storrow, A.B., Punches, B.E., Mohiuddin, K., Gentile, N.T., McGrath, M.E., van Rooij, S.J.H., Haran, J.P., Peak, D.A., Domeier, R.M., Pearson, C., Sanchez, L.D., Rathlev, N.K., Peacock, W.F., Bruce, S.E., Joormann, J., Barch, D.M., Pizzagalli, D.A., Sheridan, J.F., Harte, S.E., Elliott, J.M., Hwang, I., Petukhova, M.V., Sampson, N.A., Koenen, K.C., McLean, S.A.  Prior sleep problems and adverse post-traumatic neuropsychiatric sequelae (APNS) of motor vehicle collision in the AURORA study. Sleep. (PDF)

Olson, E.A., Pizzagalli, D.A., Rosso, I.M. (2021). Social anhedonia is associated with low social network diversity in trauma-exposed adults. Journal of Traumatic Stress, 34, 241-247. (PDF)

Peckham, A.D., Sandler, J. P., Dattolico, D., McHugh, R.K., Johnson, D.S., Björgvinsson, T., Pizzagalli, D.A., Beard, C. (2021). A pilot randomized trial of cognitive control training for urgency in an acute psychiatric sample. Behaviour Research and Therapy, 146, 103968. (PDF)

Pedersen, M.L., Ironside, M., Amemori, K.-I., McGrath, C.M., Kang, M.S., Graybiel, A.M., Pizzagalli, D.A.*, Frank, M.J.* (2021). Computational phenotyping of brain-behavior dynamics underlying approach-avoidance conflict in major depressive disorder. PLOS Computational Biology. 17(5): e1008955. https://doi.org/10.1371/journal.pcbi.1008955 [*Equal senior contributions.] (PDF)

Pizzagalli, D.A. (2021). A new chapter for Cognitive, Affective & Behavioral Neuroscience. Cognitive, Affective, & Behavioral Neuroscience, 21, 267-268. (PDF)

Reinen JM, Whitton AE, Pizzagalli DA, Slifstein M, Abi-Dargham A, McGrath PJ, Iosifescu DV, Schneier FR. (2021). Differential reinforcement learning responses to positive and negative information in unmedicated individuals with depression. European Neuropsychopharmacology, 53, 89-100. (PDF)

Robble, M.A*, Schroder, H.S.*, Kangas, B.D., Nickels, S., Breiger, M., Iturra-Mena, A., Perlo, S., Cardenas, E., Der-Avakian, A., Barnes, S.A., Leutgeb, S.,  Risbrough, V.B., Vitaliano, G., Bergman, J., Carlezon, W.A., Jr. 1, Pizzagalli, D.A. (2021). Concordant neurophysiological signatures of cognitive control in humans and rats. Neuropsychopharmacology, 46, 1252-1262. [*Co-first authors] (PDF)

Romer, A.L., Pizzagalli, D.A. (2021). Is executive dysfunction a risk marker or consequence of psychopathology? A test of executive function as a prospective predictor and outcome of general psychopathology in the Adolescent Brain Cognitive Development Study®. Developmental Cognitive Neuroscience, 51, 100994. (PDF)

Schettino, M., Ghezzi, V., Ang, Y.-S., Duda, J.M., Fagioli, S., Mennin, D.S., Pizzagalli, D.A., Ottaviani, C. (2021). Perseverative cognition in the positive valence systems: An experimental and ecological investigation. Brain Sciences. 2021, 11, 585. https://doi.org/10.3390/brainsci11050585 (PDF)

Seligowski, A.V., Reffi, A.N., Phillips, K.A., Orcutt, H.K., Auerbach, R.P., Pizzagalli, D.A., Ressler, K. J. (2021). Neurophysiological responses to safety signals and the role of cardiac vagal control. Behavioural Brain Research, 396, 112914. (PDF)

Seligowski, A.V., Steuber, E.R., Hinrichs, R., Reda, M.H., Wiltshire, C.N., Wanna, C.P., Winters, S.J., Phillips, K.A., House, S.L., Beaudoin, F.L., An, X., Stevens, J.S., Zeng, D., Neylan, T.C., Clifford, G.D., Linnstaedt, S.D., Germine, L.T., Bollen, K.A., Guffanti, G., Rauch, S.L., Haran, J.P., Storrow, A.B., Lewandowski, C., Musey, Jr. P.I., Hendry, P.L., Sheikh, S., Jones, C.W., Punches, B.E., Kurz, M.C., Murty, V.P., McGrath, M.E., Hudak, L.A., Pascual, J.L., Seamon, M.J., Datner, E.M., Chang, A.M., Pearson, C., Peak, D.A., Merchant, R.C., Domeier, R.M., Rathlev, N.K., O’Neil, B.J., Sanchez, L.D., Bruce, S.E., Miller, M.W., Pietrzak, R.H., Joormann, J., Barch, D.M., Pizzagalli, D.A., Sheridan, J.F., Luna, B., Harte, S.E., Elliot, J.M., Koenen, K.C., Kessler, R.C., McLean, S.A., Ressler, K.J., Jovanovic, T. (2021). A prospective examination of sex differences in posttraumatic autonomic functioning. Neurobiology of Stress, 15, 100384. (PDF)

Song, X., Chen, X., Yuksel, C., Yuan, J., Pizzagalli, D.A., Forester, B., Öngür, D., Du, F. (2021). Bioenergetics and abnormal functional connectivity in psychotic disorders. Molecular Psychiatry, 26, 2483-2492. (PDF)

Steuber, E.R., Seligowski, A.V., Roeckner, A.R., Reda, M., Lebois, L.A.M., van Rooij, S.J.H., Murty, V.P., Ely, T.D., Bruce, S.E., House, S.L., Beaudoin, F.L., An, X., Zeng, D., Neylan, T.C., Clifford, G.D. Linnstaedt, S.D., Germine, L.T., Rauch, S.L., Lewandowski, C., Sheikh, S., Jones, C.W., Punches, B.E., Swor, R.A., McGrath, M.E., Hudak, L.A., Pascual, J.L., Chang, A.M., Pearson, C., Peak, D.A., Domeier, R.M., O’Neil, B.J., Rathlev, N.K., Sanchez, L.D., Pietrzak, R.H., Joormann, J., Barch, D,M., Pizzagalli, D.A., Elliott, J.M., Kessler, R.C., Koenen, K.C., McLean, S.A., Ressler, K.J., Jovanovic, T., Harnett, N.G., Stevens, J.S. (2021). Thalamic volume and fear extinction interact to predict acute posttraumatic stress severity. Journal of Psychiatric Research, 141, 325-332. (PDF)

Stevens, J.S., Harnett, N.G., Lebois, L.A.M., van Rooij, S.J.H. Ely, T.D., Roeckner, A., Vincent, S., Beaudoin, F.L., An, X., Zeng, D., Neylan, T.C., Clifford, G.D., Linnstaedt, S.D., Germine, L.T., Rauch, S.L., Lewandowski, C., Storrow, A.B., Hendry, P.L., Sheikh, S., Musey, P.I Jr., Haran, J.P., Jones, C.W., Punches, B.E., Lyons, M.S., Kurz, M.C., McGrath, M.E., Pascual, J.L., Datner, E.M., Chang, A.M., Pearson, C., Peak, D.A., Domeier, R.M., O’Neil, B.J., Rathlev, N.K., Sanchez, L.D., Pietrzak, R.H., Joormann, J., Barch, D.M., Pizzagalli, D.A., Sheridan, J.F., Luna, B., Harte, S.E., Elliott, J.M., Murty, V.P., Jovanovic, T., Bruce, S.E., House, S.L., Kessler, R.C., Koenen, K.C., McLean, S.A., Ressler, K.J. (2021). Brain-based biotypes of psychiatric vulnerability in the acute aftermath of trauma. American Journal of Psychiatry, 178, 1037-1049. (PDF)

Umemoto, A., Panier, L.Y.X., Cole, S.L., Kayser, J., Pizzagalli, D.A., Auerbach, R.P. (2021). Resting posterior alpha power and adolescent major depressive disorder. Journal of Psychiatric Research, 141, 233-240. (PDF)

Wang, K.S., Brown, K., Frederick, B.B., Moran, L.V., Olson, D., Pizzagalli, D.A., Kaiser, R.H., Janes, A.C. (2021). Nicotine acutely alters temporal properties of resting brain states. Drug and alcohol Dependence, 226, 108846. (PDF)

Webb, C.A., Auerbach, R.P., Bondy, E., Stanton, C.H., Appleman, L., Pizzagalli, D.A. (2021). Reward-related neural predictors and mechanisms of symptom change in cognitive behavioral therapy for depressed adolescent girls. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 6, 39-49. (PDF) (Editorial)

Webb, C.A., Israel, E.S., Belleau, E., Appleman, L., Forbes, E.E., Pizzagalli, D.A (2021). Mind-wandering in adolescents predicts worse affect and is linked to aberrant default mode network – salience network connectivity. Journal of the American Academy of Child and Adolescent Psychiatry, 60, 377-387. (PDF)

Whitton, A.E., Kumar, P., Treadway, M.T., Rutherford, A.V., Ironside, M.L., Foti, D., Fitzmaurice, G., Du, F., Pizzagalli, D.A. (2021). Mapping disease course across the mood disorder spectrum through a Research Domain Criteria (RDoC) framework. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 6, 706-715. (PDF)

Whitton, A.E., Rabinovich, N.A., Lindt, J.D., Pergadia, M.L., Pizzagalli, D.A., Gilbert, D.G. (2021). Genetic and depressive traits moderate the reward-enhancing effects of acute nicotine in young light smokers. Nicotine & Tobacco Research, 23, 1779-1786. (PDF)

Wooldridge, L.M., Bergman, J., Pizzagalli, D.A., Kangas, B.D. (2021). Translational assessments of reward responsiveness in the marmoset. International Journal of Neuropsychopharmacology, 24, 409-418. (PDF)

Wu, W., Pizzagalli, D.A., Trivedi, M.H., Etkin, A. (2021). Reply to: EEG-based model and antidepressant response. Nature Biotechnology, 39, 28-29. (PDF)

Yang, X.*, Kumar, P.*, Nickerson, L.D., Du, Y., Wang, M., Chen, Y., Li, T., Pizzagalli, D.A.ǂ, Ma, X.ǂ (2021). Identifying subgroups of major depressive disorder using brain structural covariance networks and mapping of associated clinical and cognitive variables. Biological Psychiatry: Global Open Science, 1, 135-145. [* Co-first authors; ǂ Equal senior contributions] (PDF)

Ziobrowski, H.N., Kennedy, C.J., Ustun, B., House, S.L., Beaudoin, F.L., An, X., Stevens, J.S., Zeng, D., Neylan, T.C., Clifford, G.D., Jovanovic, T., Linnstaedt, S.D., Germine, L.T., Bollen, K.A., Rauch, S.L., Haran, J.P., Storrow, A.B., Lewandowski, C., Musey, P.I. Jr., Hendry, P.L., Sheikh, S., Jones, C.W., Punches, B.E., Lyons, M.S., Murty, V.P., McGrath, M.E., Pascual, J.L., Seamon, M.J., Datner, E.M., Chang, A.M., Pearson, C., Peak, D.A., Jambaulikar, G., Merchant, R.C., Domeier, R.M., Rathlev, N.K., O’Neil, B.J., Sergot, P., Sanchez, L.D., Bruce, S.E., Pietrzak, R.H., Joormann, J., Barch, D.M., Pizzagalli, D.A., Sheridan, J.F., Harte, S.E., Elliott, J.M., Petukhova, M., Sampson, N.A., Puac-Polanco, V., Lee, S., van Rooij, S.J., Koenen, K.C., Ressler, K.J., McLean, S.A., Kessler, R.C. (2021). Development and validation of a model to predict posttraumatic stress disorder and major depression after a motor vehicle collision. JAMA Psychiatry, 78, 1228-1237. (PDF)

Zürcher, N.R., Walsh, E.C., Phillips, R.D., Cernasov, P.M., Tseng, C-E. J., Dharanikota, A., Smith, E., Li, Z., Kinard, J.L., Bizzell, J.C., Greene, R.K., Dillon, D., Pizzagalli, D.A., Izquierdo-Garcia, D., Truong, K., Lalush, D., Hooker, J.M., Dichter, G.S. (2021). A simultaneous [11C]Raclopride Positron Emission Tomography and functional Magnetic Resonance Imaging investigation of striatal dopamine binding in autism. Translational Psychiatry 11, 33 (2021). https://doi.org/10.1038/s41398-020-01170-0 (PDF)

Pizzagalli Lab (LATN)

2020 Publications

Ang, Y-S., Frontero, N., Belleau, E., Pizzagalli, D.A. (2020). Disentangling vulnerability, state and trait features of neurocognitive impairments in depression. Brain, 143, 3865-3877. (PDF)

Ang, Y-S, Kaiser, R., Deckersbach, T., Almeida, J., Phillips, M.L., Chase, H.W., Webb, C.A, Parsey, R., Fava, M., McGrath P., Weissman, M., Adams, P., Deldin, P., Oquendo, M.A., McInnis, M.G., Carmody, T., Bruder, G., Cooper, C.M., Chin Fatt, C.R., Trivedi, M.H., Pizzagalli, D.A. (2020). Pretreatment reward sensitivity and frontostriatal resting-state functional connectivity are associated with response to bupropion after sertraline non-response. Biological Psychiatry, 88, 657-667. (PDF)

Browning, M., Carter, C.S.,  Chatham, C., Den Ouden, H., Gillan, C.M., Baker, J.T.,  Chekroud, A.M.,  Cools, R.,  Dayan, P,  Gold, J., Goldstein, R..Z, Hartley, C.A., Kepecs, A.,  Lawson, R.P.,  Mourao-Miranda, J.,  Phillips, M.L.,  Pizzagalli, D.A., Powers, A.,  Rindskopf, D.,  Roiser, J.P., Schmack, K.,  Schiller, D., Sebold, M.,  Stephan, K.E., Franky, M.J., Huys, Q.,  Paulus, M.  (2020). Realizing the clinical potential of computational psychiatry: Report from the Banbury Center Meeting, February 2019. Biological Psychiatry. 2020; 88:e5-e10. (PDF)

Carvalho, A.F, Solmi, M., Sanches, M., Machado, M.O., Stubbs, B., Ajnakina, O., Sherman, C., Sun, Y.R., Liu, C.S., Brunoni, A.R., Pigato, G., Fernandes, B.S., Bortolato, B., Husain, M.I., Dragioti, E., Firth, J., Cosco, T.D., Maes, M., Berk, M., Lanctôt, K.L., Vieta, E., Pizzagalli, D.A., Smith, L., Fusar-Poli, P., Kurdyak, P.A., Fornaro, M., Rehm, J., Herrmann, N. (2020). Evidence-based umbrella review of 162 peripheral biomarkers for major mental disorders. Translational Psychiatry. 2020 May 18;10(1):152. doi: 10.1038/s41398-020-0835-5. (PDF)

Hubbard, N.A., Siless, V., Frosch, I., Goncalves, M., Lo, N., Wang, J., Bauer, C.C.C., Conroy, K., Cosby, E., Hay, A., Jones, R., Pinaire, M., Vaz De Souza, F., Vergara, G., Ghosh, S., Henin, A., Hirshfeld-Becker, D.R., Hofmann, S.G., Auerbach, R.P., Pizzagalli, D.A., Yendiki, A., Gabrieli, J.D.E., Whitfield-Gabrieli, S. (2020). Brain function and clinical characterization in the Boston Adolescent Neuroimaging of Depression and Anxiety study. NeuroImage Clinical, 27, 102240. (PDF)

Ironside, M*., Amemori, K-I*., McGrath, C.L., Pedersen, M.L., Kang, M.S., Amemori, S., Frank, M.J., Graybiel, A.M., Pizzagalli, D.A. (2020). Approach-avoidance conflict in major depression: Congruent neural findings in human and non-human primates. Biological Psychiatry, 87(5), 399-408. * Equal contribution (PDF)

Ironside, M., Admon, R., Maddox, S.A., Mehta, M., Douglas, S., Olson, D.P., Pizzagalli, D.A. (2020). Inflammation and depressive phenotypes: Evidence from medical records from over 12,000 patients and brain morphology. Psychological Medicine, 50, 2790-2798. (PDF)

Javaras, K.N., Pizzagalli, D.A. (2020). Neural insensitivity to the effects of hunger: A potential mechanism underlying persistent dietary restriction in Anorexia Nervosa? American Journal of Psychiatry, 177, 567-569 [Invited editorial] (PDF)

Kangas, B.D., Wooldridge, L.M., Luc, O.T., Bergman, J., Pizzagalli, D.A. (2020). Empirical validation of a touchscreen probabilistic reward task in rats. Translational Psychiatry, 10, 285. doi.org/10.1038/s41398-020-00969-1 (PDF)

Kim, M., Mawla, I., Albrecht, D.S., Admon, R., Torrado-Carvajal, A., Bergan, C., Protsenko, E., Kumar, P., Edwards, R.E., Sahaa, A., Napadow, V., Pizzagalli, D.A., Loggia, M.L. (2020). Striatal hypofunction as a neural correlate of mood alterations in chronic pain patients. NeuroImage, 211, 116656. (PDF)

Krystal, A.D., Pizzagalli, D.A., Smoski, M., Mathew, S.J., Nurnberger, J., Jr., Lisanby, S.H., Iosifescu, D., Murrough, J.W., Yang, H., Weiner, R.D., Calabrese, J.R., Sanacora, G., Hermes, G., Keefe, R.S.E., Song, A., Goodman, W., Szabo, S.T., Whitton, A.E., Gao., K.,  Potter, W.Z. (2020). A randomized proof-of-mechanism trial applying the ‘fast-fail’ approach to evaluating kappa-opioid antagonism as a treatment for anhedonia. Nature Medicine, 26, 760-768. (PDF)

Lawlor, V.M., Webb, C.A., Wiecki, T.V., Frank, M.J., Trivedi, M., Pizzagalli, D.A., Dillon, D.G. (2020). Dissecting the impact of depression on decision-making. Psychological Medicine, 50, 1613-1622. (PDF)

Liu, Y., Admon, R., Mellem, M.S., Belleau, E.M., Kaiser, R.H., Clegg, R., Beltzer, M., Goer, F., Vitaliano, G., Ahammad, P., Pizzagalli, D.A. (2020). Machine learning identifies large-scale reward-related activity modulated by dopaminergic enhancement in major depression. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 5, 163-172. (PDF)

McLean, S.A., Ressler, K., […], Pizzagalli, D.A., […], Kessler, R. (2020). The AURORA study: A longitudinal, multimodal library of brain biology and function after traumatic stress exposure. Molecular Psychiatry, 25, 283-296 [50th of 68 authors]. (PDF)

Molokotos, E., Peechatka, A.L., Wang, K.S., Pizzagalli, D.A., Janes, A.C. (2020). Caudate reactivity to smoking cues is associated with increased responding to monetary reward in nicotine-dependent individuals. Drug and Alcohol Dependence, 209, 107951. (PDF)

Murphy, M, Whitton, A.E., Deccy, S., Ironside, M.I., Rutherford, A., Beltzer., M., Sacchet, M., Pizzagalli, D.A. (2020). Abnormalities in electroencephalographic microstates are state and trait markers of major depressive disorder. Neuropsychopharmacology. 2020 Jun 26. doi: 10.1038/s41386-020-0749-1. Online ahead of print. (PDF)

Olson, E.A., Overbey, T.A., Ostrand, C.G., Pizzagalli, D.A., Rauch, S.L., Rosso, I.M. (2020). Childhood maltreatment experiences are associated with altered diffusion in occipito-temporal white matter pathways. Brain and Behavior. 2020 Jan;10(1):e01485. doi: 10.1002/brb3.1485 (PDF)

Petibon, Y., Alpert, N.M., Ouyang, J., Pizzagalli, D.A., Cusin, C., Fava, M., El Fakhri, G., Normandin, M.D. (2020). PET imaging of neurotransmission using direct parametric reconstruction. NeuroImage, 221, 117154. (PDF)

Piantadosi, S.C., Pizzagalli, D.A., Bruchas, M.R. (2020). The complex role of nociceptin signaling in stress: Clarity through neuroimaging? Biological Psychiatry, 87, 489-491 [Invited commentary] (PDF)

Pizzagalli, D.A. (2020). Depression: Harnessing biology and technology for the next generation of Treatments. Harvard Review of Psychiatry, 28, 1-3 [Editorial, Special Issue]. (PDF)

Pizzagalli, D.A., Smoski, M., Ang, Y-S., Whitton, A.E., Sanacora, G., Mathew, S.J., Nurnberger, J. Jr, Lisanby, S.H., Iosifescu, D.V., Murrough, J.W., Yang, H., Weiner, R.D., Calabrese, J.R., Goodman, W., Potter, W.Z., Krystal, A.D. (2020). Selective kappa opioid antagonism ameliorates anhedonic behavior: Evidence from the Fast-Fail Trial in mood and anxiety spectrum disorders (FAST-MAS). Neuropsychopharmacology, 45, 1656-1663. (PDF)

Reilly, E.E., Whitton, A.E., Pizzagalli, D.A., Rutherford, A.V., Stein, M.B., Paulus, M.P., Taylor, C.T. (2020). Diagnostic and dimensional evaluation of implicit reward learning in social anxiety disorder and major depression. Depression & Anxiety, 37, 1221-1230. (PDF)

Rolle, C.E., Fonzo, G.A., Wu, W., Toll, R., Jha, M.K., Cooper, C., Chin-Fatt, C., Pizzagalli, D.A., Trombello, J.M., Deckersbach, T., Fava, M., Weissman, M.M., Trivedi, M.H., Etkin, A. (2020). Cortical connectivity moderators of antidepressant vs placebo treatment response in Major Depressive Disorder: Secondary analysis of a randomized clinical trial. JAMA Psychiatry, 77, 397-408. (PDF)

Schroder, H.S., Nickels, S., Cardenas, E., Breiger, M., Perlo, S., Pizzagalli, D.A. (2020). Optimizing assessments of post-error slowing: A neurobehavioral investigation of a Flanker Task. Psychophysiology. 57(2), E13473-N/a. (PDF)

Siless, V., Hubbard, N.A., Wang J., Jones, R., Lo, N., Bauer, C.C.C., Goncalves, M., Frosch, I., Norton, D., Vergara, G., Conroy, K., Vaz De Souza, F., Rosso, I.M., Wickham, A.H., Cosby, E.A., Hirshfeld-Becker, D., Pizzagalli, D.A., Henin, A., Hofmann, S.G., Auerbach, R.P., Ghosh, S., Gabrieli, J., Whitfield-Gabrieli, S., Yendiki, A. (2020). Image acquisition and quality assurance in the Boston Adolescent Neuroimaging of Depression and Anxiety study. NeuroImage Clinical, 26, 102242. (PDF)

Smith, E.E., Tenke, C.E., Deldin, P.J., Trivedi, M.H., Weissman, M.M., Auerbach, R.P., Bruder, G.E., Pizzagalli, D.A., Kayser, J. (2020). Frontal theta and posterior alpha in resting EEG: A critical examination of convergent and discriminant validity. Psychophysiology. 2020;57:e13483.https://doi.org/10.1111/psyp.13483. (PDF)

Wang, K.S., Zegel, M., Molokotos, E., Moran, L.V., Olson, D.P., Pizzagalli, D.A., Janes, A.C. (2020). The acute effects of nicotine on corticostriatal responses to distinct phases of reward processing. Neuropsychopharmacology, 45, 1207-1214. (PDF)

Whitton, A.E., Reinen, J.M., Slifstein, M., Ang, Y.-S., McGrath, P.J., Iosifescu, D.V., Abi-Dargham, A., Pizzagalli, D.A.*, & Schneier, F.R.* (2020). Baseline reward processing and ventrostriatal dopamine function are associated with pramipexole response in depression. Brain, 143, 701-710. [*Equal senior contribution] (PDF)

Wu, W., Zhang, Y., Jiang, J., Lucas, M.V., Fonzo, G.A., Rolle, C.E., Cooper, C., Chin-Fatt, C., Krepel, N., Cornelssen, C.A., Wright, R., Toll, R.T., Trivedi, H.M., Monuszko, K., Caudle, T.L., Sarhadi, K., Jha, M.K., Trombello, J.M., Deckersbach, T., Adams, P., McGrath, P.J., Weissman, M.M., Fava, M., Pizzagalli, D.A., Arns, M., Trivedi, M.H., Etkin, A. (2020). An electroencephalographic signature predicts antidepressant response in Major Depression. Nature Biotechnology, 38, 439-447. (PDF)

Yapici Eser, H., Appadurai, V., Yasemin Eren, C., Yazici, D., Chen, C.-Y., Ongur, D., Pizzagalli, D.A., Werge, T., Hall, M.-H. (2020). Association between GLP-1 receptor gene polymorphisms with reward learning, anhedonia, and depression diagnosis. Acta Neuropsychiatrica, 32, 218-225. (PDF)

Pizzagalli Lab (LATN)

2019 Publications

Aas, M., Pizzagalli, D.A., Anderssen, J.F. Collier Høegh, M., Reponen, E.J., Huflåtten, I.B., Buchmann, C.B., Steen, N.E., Ueland, T., Melle, I., Agartz, I., Andreassen, O.E. (2019). Elevated hair cortisol is associated with childhood maltreatment and cognitive impairment in schizophrenia and in bipolar disorders. Schizophrenia Research, 213, 65-71. (PDF)

Ang, YS, Pizzagalli, D.A. (2019). Understanding personal control and the brain reward system for psychopathology is challenging but important. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4, 105-107. (PDF)

Auerbach, R.P, Pizzagalli, D.A. (2019). Localized MRS reliability of in vivo glutamate at 3 T in shortened scan times: A feasibility study – Efforts to improve rigor and reproducibility. NMR in Biomedicine. 2019 Mar 21;:e4093. (PDF)

Auerbach, R.P, Pagliaccio, D., Pizzagalli, D.A. (2019). Towards an improved understanding of anhedonia in youth. JAMA Psychiatry, 76, 571-573. (PDF)

Baker, J.T., Dillon, D.G., Patrick, L.M., Roffman, J.L., Brady, R.O., Jr., Pizzagalli, D.A., Öngür, D., Holmes, A.J. (2019). Functional connectomics of affective and psychotic pathology. Proceedings of the National Academy of Sciences USA, 116, 9050-9059. (PDF)

Bakker, J.M., Goossens, L., Kumar, P., Lange, I., Michielse, S., Schruers, K., Bastiaansen, J., Lieverse, R., Marcelis, M., van Amelsvoort, T., van Os, J., Myin-Germeys, I., Pizzagalli, D.A., Wichers, M. (2019). From lab to life: Associating brain reward processing with motivated behaviour in daily life. Psychological Medicine, 49, 2441-2451. (PDF)

Belleau, E.L., Treadway, M.T., Pizzagalli, D.A. (2019). The impact of stress and major depressive disorder on hippocampal and medial prefrontal cortex morphology. Biological Psychiatry, 85, 443-453. (PDF)

Boyle, C.C., Kuhlman, K.R., Dooley, L.N., Haydon, M.D., Robles, T.F., Ang, Y-S., Pizzagalli, D.A., Bower, J.E. (2019). Inflammation and dimensions of reward processing following exposure to the influenza vaccine. Psychoneuroendocrinology, 102, 16-23. (PDF)

Chen, X., Fan, X., Hu, Y., Zuo, C., Gabrieli, S., Holt, D., Gong, Q., Yang, Y., Pizzagalli, D.A., Du, F., Ongur, D. (2019). Regional GABA concentrations modulate inter-network resting-state functional connectivity. Cerebral Cortex, 29, 1607-1618. (PDF)

Finan, P.H., Whitton, A.E., Letzen, J.E., Remeniuk, B., Robinson, M.L., Irwin, M.R., Pizzagalli, D.A., Smith, M.T. (2019). Experimental sleep disruption and reward learning: Moderating role of positive affect responses. Sleep. 2019 May 1;42(5). pii: zsz026. doi: 10.1093/sleep/zsz026. (PDF)

Green, I.W., Pizzagalli, D.A., Admon, R., Kumar, P. (2019). Anhedonia modulates the effects of positive mood induction on reward-related brain activation. NeuroImage, 193, 115-125. (PDF)

Guffanti, G., Kumar, P., Admon, R., Treadway, M.T., Hall, M., Mehta, M., Douglas, S., Arulpragasam, A.R., Pizzagalli, D.A. (2019). Depression genetic risk score is associated with anhedonia-related markers across units of analysis. Translational Psychiatry, 2019 Sep 19;9(1):236. doi: 10.1038/s41398-019-0566-7. (PDF)

Kaiser, R.H., Kang, M., Lew, Y., Van Der Feen, J., Aguirre, B., Clegg, R., Goer, F., Esposito, E., Auerbach, R. P., Hutchison, R.M., Pizzagalli, D.A. (2019). Abnormal frontoinsular-default network dynamics in adolescent depression and rumination: A preliminary resting-state co-activation pattern analysis. Neuropsychopharmacology, 44, 1604-1612. (PDF)

Kaiser, R.H., Peterson, E., Kang, M-S., Van Der Feen, J., Aguirre, B., Clegg, R., Goer, F., Esposito, E.C., Auerbach, R.P., Pizzagalli, D.A. (2019). Frontoinsular network markers of current and future adolescent mood health. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4(8):715-725. (PDF)

Krystal, A.D., Pizzagalli, D.A., Mathew, S.J., Sanacora, G., Keefe, R., Song, A., Calabrese, J., Goddard, A., Goodman, W., Lisanby, S.H., Smoski, M., Weiner, R., Iosifescu, D., Nurnberger, J., Szabo, S., Murrough, J., Shekhar, A., Potter, W. (2019). The first implementation of the NIMH FAST-FAIL approach to psychiatric drug development. Nature Reviews Drug Discovery, 18, 82-84. (PDF)

Kumar, P., Pisoni, A., Bondy, E., Kremens, R., Singleton, P., Pizzagalli, D.A.*, Auerbach, R.P.* (2019). Delineating the social valuation network in adolescents. Social Cognitive and Affective Neuroscience, 14, 1159-1166. [*Equal senior contribution] (PDF)

Lawlor, V.M., Webb, C.A., Wiecki, T.V., Frank, M.J., Trivedi, M., Pizzagalli, D.A., Dillon, D.G. (2019). Dissecting the impact of depression on decision-making. Psychological Medicine. 2019 Jul 8:1-10. doi: 10.1017/S0033291719001570. (PDF)

Liao, A., Walker, R., Carmody, T.J., Cooper, C., Shaw, M.A., Grannemann, B.D., Adams, P.A., Bruder, G.E., McInnis, M.G., Webb, C.A., Dillon, D.G., Pizzagalli, D.A., Phillips, M.L., Kurian, B.T., Fava, M., Parsey, R.V., McGrath, P.J., Weissman, M.M., Trivedi, M.H. (2019). Anxiety and anhedonia in depression: Associations with neuroticism and cognitive control. Journal of Affective Disorders, 245, 1070-1078. (PDF)

Lincoln, S.H, Pisoni, A, Bondy, E., Kumar, P., Singleton, P, Hajcak, G., Pizzagalli, D.A., Auerbach, R.P. (2019). Altered reward processing following an acute social stressor in adolescents. PLos One. 2019 Jan 4;14(1):e0209361. doi: 10.1371/journal.pone.0209361. eCollection 2019. (PDF)

McCarthy, J.M., Dumais, K.M., Zegel, M., Pizzagalli, D.A., Olson, D.P., Moran, L.V., Janes, A.C. (2019). Sex differences in tobacco smokers: Executive control network and frontostriatal connectivity. Drug and Alcohol Dependence, 195, 59-65. (PDF)

Olson, E.A., Kaiser, E.H., Pizzagalli, D.A., Rauch, S.L., Rosso, I.M. (2019). Regional prefrontal resting state functional connectivity in Posttraumatic Stress Disorder. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 4, 390-398. (PDF)

Olson, E.A., Overbey, T.A., Ostrand, C.G., Pizzagalli, D.A., Rauch, S.L., Rosso, I.M. (2019). Childhood maltreatment experiences are associated with altered diffusion in occipito-temporal white matter pathways. Brain and Behavior. 2019;00:e01485. https://doi.org/10.1002/brb3.1485 (PDF)

Pillai, R.L.I, Huang, C., LaBella, A., Zhang, M., Yang, J., Trivedi, M., Weissman, M., McGrath, P., Fava, M., Kurian, B., Cooper, C., McInnis, M., Oquendo, M.A., Pizzagalli, D.A., Parsey, R.V., DeLorenzo, C. (2019). Examining raphe-amygdala structural connectivity as a biological predictor of SSRI response. Journal of Affective Disorders, 256, 8-16. (PDF)

Pizzagalli, D.A., Berretta, S., Wooten, D., Goer, F., Pilobello, K.T., Kumar, P., Murray, L., Beltzer, M., Boyer-Boiteau, A., Alpert, N., El Fakhri, G., Mechawar, N., Vitaliano, G., Turecki, G., Normandin, M. (2019). Assessment of striatal dopamine transporter binding in individuals with major depressive disorder: In vivo positron emission tomography and postmorten evidence. JAMA Psychiatry, 76, 854-861. (PDF)

Reich, D.B., Belleau, E.L., Temes, C.M., Gonenc, A., Pizzagalli, D.A., Gruber, S.A. (2019). Amygdala resting state connectivity differences between Bipolar II and Borderline Personality Disorders. Neuropsychobiology, 78, 229-237.

Smith, E.E., Tenke, C.E., Deldin, P.J., Trivedi, M.H., Weissman, M.M., Auerbach, R.P., Bruder, G.E., Pizzagalli, D.A., Kayser, J. (2019). Frontal theta and posterior alpha in resting EEG: A critical examination of convergent and discriminant validity. Psychophysiology. 2019;00:e13483. https ://doi.org/10.1111/psyp.13483 (PDF)

Sperl, M.F.J., Panitz, C., Rosso, I.M., Dillon, D.G., Kumar, P., Hermann, A., Whitton, A.E., Hermann, C., Pizzagalli, D.A., Mueller, E.M. (2019). Fear extinction recall modulates human fronto-medial theta and amygdala activity. Cerebral Cortex, 29, 701-715. (PDF)

Ulke, C., Tenke, C.E., Kayser, J., Sander, C., Böttger, D., Wong, L.Y.X., Alvarenga, J.A., Fava, M., McGrath, P.J., Deldin. P.J., Mcinnis. M.G.., Trivedi, M.H., Weissman, M.M., Pizzagalli, D.A., Hegerl, U., Bruder, G.E. (2019). Resting EEG measures of brain arousal in a multisite study of major depression. Clinical EEG & Neuroscience, 50, 3-12. (PDF)

Webb, C.A., Stanton, C.H., Bondy, E., Singleton, P., Pizzagalli, D.A., Auerbach, R.P. (2019). Cognitive versus behavioral skills in CBT for depressed adolescents: Disaggregating within-patient versus between-patient effects on symptom change. Journal of Consulting and Clinical Psychology, 87, 484-490. (PDF)

Webb, C.A., Trivedi, M.D., Cohen, C., Dillon, D.G., Fournier, F., Goer, F., Fava, M., McGrath, P.J., Weissman, M., Parsey, R., Adams, P., Trombello, J.M., Cooper, C., Deldin, P., Oquendo, M.A., McInnis, M.G., Huys, Q., Bruder, G., Kurian, B., Jha, M., DeRubeis, R.J., Pizzagalli D.A. (2019). Personalized prediction of antidepressant versus placebo response: Evidence from the EMBARC trial. Psychological Medicine, 49(7), 1118-1127. (PDF)

Whitton, A.E., Green, A.I., Pizzagalli, D.A., Roth, R.M., Williams, J.M., Brunette, M.F. (2019). Potent dopamine D2 antagonists block the reward-enhancing effects of nicotine in smokers with schizophrenia. Schizophrenia Bulletin, 45, 1300-1308. (PDF)

Whitton, A.E., Webb, C.A., Dillon, D.G., Kayser, J., Rutherford, A., Goer, F., Fava, M., McGrath, P., Weissman, M., Parsey, R., Adams, P., Trombello, J.M., Cooper, C., Deldin, P., Oquendo, M.A., McInnis, M.G., Carmody, T., Bruder, G., Trivedi, M.H., Pizzagalli, D.A. (2019). Pre-treatment rostral anterior cingulate cortex connectivity with salience network predicts depression recovery: Findings from the EMBARC randomized clinical trial. Biological Psychiatry, 85, 872-880. (PDF)

Zorowitz, S., Rockhill, A.P., Ellard, K.K., Link, K.E., Herrington, T., Pizzagalli, D.A., Widge, A.S., Deckersbach, T., Dougherty, D.D. (2019). The neural basis of approach-avoidance conflict: A model based analysis. eNeuro. 2019 Aug 8;6(4). pii: ENEURO.0115-19.2019. doi: 10.1523/ENEURO.0115-19.2019. Print 2019 Jul/Aug. (PDF)

Pizzagalli Lab (LATN)

2018 Publications

Bartlett, E.A., DeLorenzo, C., Sharma, P., Yang, J., Zhang, M., Petkova, E., Weissman, M., McGrath, P.J., Fava, M., Ogden, T., Kurian, B.T., Malchow, A., Cooper, C.M., Trombello, J., McInnis, M., Adams, P., Oquendo, M.A., Pizzagalli, D.A., Trivedi, M., Parsey, R.V. (2018). Pre- and early-treatment cortical thickness is associated with SSRI treatment response in Major Depressive Disorder. Neuropsychopharmacology, 43, 2221-2230. (PDF)

Chen, X., Fan, X., Hu, Y., Zuo, C., Gabrieli, S., Holt, D., Gong, Q., Yang, Y., Pizzagalli, D.A., Du, F., Ongur, D. (in press). Regional GABA concentrations modulate inter-network resting-state functional connectivity. Cerebral Cortex. 2018 Mar 28. doi: 10.1093/cercor/bhy059. [Epub ahead of print] (PDF)

Der-Avakian, A., Pizzagalli, D.A. (2018). Translational assessments of reward and anhedonia: A tribute to Athina Markou. Biological Psychiatry, 83, 932-939. (PDF)

Dillon, D.G.*, Gonenc, A.*, Belleau, E., Pizzagalli, D.A. (2018). Depression is associated with dimensional and categorical effects on white matter pathways. Depression and Anxiety, 35, 440–447 [*Co-first authors] (PDF)

Dillon, D.G., Pizzagalli, D.A. (2018). Mechanisms of memory disruption in depression. Trends in Neurosciences, 41, 137-149. (PDF)

Ironside, M., Kumar. P., Kang, M.-S., Pizzagalli, D.A. (2018). Brain mechanisms mediating effects of stress on reward sensitivity. Current Opinion in Behavioral Sciences, 22, 106-113. (PDF)

Janes, A.C., Zegel, M., Ohashi, K. Betts, J., Molokotos, E., Olson, D., Moran, L., Pizzagalli, D.A. (2018). Nicotine normalizes cortico-striatal connectivity in non-smoking individuals with major depressive disorder. Neuropsychopharmacology, 43, 2445-2451. (PDF)

Kaiser, R.H., Clegg, R., Goer, F., Pechtel, P., Beltzer, M., Vitaliano, G., Olson, D.P. Teicher, M.H., Pizzagalli, D.A. (2018). Childhood stress, grown-up brain networks: Corticolimbic correlates of threat-related early life stress and adult stress response. Psychological Medicine, 48, 1157-1166. (PDF)

Kaiser, R.H., Snyder, H.R., Goer, F., Clegg, R., Pizzagalli, D.A. (2018). Attention bias in rumination and depression: Cognitive mechanisms and brain networks. Clinical Psychological Science, 6, 765-782. (PDF)

Kaiser, R.H., Treadway, M.T.*, Wooten, D.W.*, Kumar, P.*, Goer, F., Murray, L., Beltzer, M., Pechtel, P., Whitton, A.E., Cohen, A.L., Alpert, N.M., El Fakhri, G., Normandin, M.D., Pizzagalli, D.A. (2018). Frontostriatal and dopamine markers of individual differences in reinforcement learning: A multi-modal investigation. Cerebral Cortex, 28, 4281-4290 [*Equal contributions] (PDF)

Kumar, P., Goer, F., Murray, L., Dillon, D.G., Beltzer, M.L., Cohen, A.L., Brooks, N.H., Pizzagalli, D.A. (2018). Impaired reward prediction error encoding and striatal-midbrain connectivity in depression. Neuropsychopharmacology, 43(7), 1581–1588. (PDF)

Moran, L.V., Stoeckel, L.E., Wang, K., Caine, C.E., Villafuerte, R., Calderon, V., Baker, J.T., Ongur, D., Janes, A.J., Evins, A.E.*, Pizzagalli, D.A.* (2018). Nicotine-induced activation of caudate and anterior cingulate cortex in response to errors in schizophrenia. Psychopharmacology, 235, 789-802. [*Equal senior contributions.] (PDF)

Moran, L.V., Stoeckel, L.E., Wang, K., Caine, C.E., Villafuerte, R., Calderon, V., Baker, J.T., Ongur, D., Janes, A.C., Pizzagalli, D.A.*, Evins, A.E.* (2018). Nicotine increases activation to anticipatory valence cues in anterior insula and striatum. Nicotine & Tobacco Research, 20, 851-858 [*Equal senior contributions.] (PDF)

Olson, E.A., Kaiser, R.H., Pizzagalli, D.A., Rauch, S.L., Rosso, I.M. (2018). Anhedonia in trauma-exposed individuals: functional connectivity and decision-making correlates. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 3, 959-967. (PDF)

Pereira, L.P., Köhler, C.A., Stubbs, B., Miskowiak, K.W., Morris, G., de Freitas, B.P., Thompson, T., Fernandes, B.S., Brunoni, A.R., Maes, M., Pizzagalli, D.A., Carvalho, A.F. (2018). Imaging genetics paradigms in depression research: Systematic review and meta-analysis. Progress in Neuropsychopharmacology & Biological Psychiatry, 86, 102-113. (PDF)

Pizzagalli, D.A.*, Webb, C.A.*, Dillon, D.G., Tenke, C.E., Kayser, J., Goer, F., Fava, M., McGrath, P., Weissman, M., Parsey, R., Adams, P., Trombello, J., Cooper, C., Deldin, P., Oquendo, M.A., McInnis, M.G., Carmody, T., Bruder, G., Trivedi, M.H. (2018). Pretreatment rostral anterior cingulate cortex activity in relation to symptom improvements in depression: A randomized clinical trial. JAMA Psychiatry, 75, 547-554. [*Equal contributions]. (PDF)

Schneier, F.R., Slifstein M., Whitton, A.E., Pizzagalli, D.A., Reinen, J., McGrath, P.J., Iosifescu, D.V., Abi-Dargham, A. (2018). Dopamine release in antidepressant-naïve major depressive disorder: a multimodal [11C]-(+)-PHNO positron emission tomography and functional magnetic resonance imaging study. Biological Psychiatry, 84, 563-573. (PDF)

Tan, A., Costi, S., Morris, L.S., Van Dam, N.T., Kautz, M., Whitton, A.E., Friedman, A.K., Collins, K.A., Ahle, G., Chadha, N., Do, B., Pizzagalli, D.A., Iosifescu, D.V., Nestler, E.J., Han, M.-H., Murrough, J.W. (2018). Effects of the KCNQ channel opener ezogabine on functional connectivity of the ventral striatum and clinical symptoms in patients with major depressive disorder. Molecular Psychiatry. 2018 Nov 1. doi: 10.1038/s41380-018-0283-2.

Trivedi, M.H., South, C., Jha, M.K., Rush, A.J., Cao, J., Kurian, B., Phillips, M., Pizzagalli, D.A., Trombello, J.M., Oquendo, M.A., Cooper, C., Dillon, D.G., Webb, C., Grannemann, B.D., Bruder, G., McGrath, P.J., Parsey, R., Weissman, M., Fava, M. (2018). A novel strategy to identify placebo responders: Prediction index of clinical and biological markers in the EMBARC trial. Psychotherapy and Psychosomatics, 87, 285-295. (PDF)

Trombello, J.M., Pizzagalli, D.A., Weissman, M., Grannemann, B.D., Cooper, C.M., Greer, T.L., Malchow, A.L., Jha, M.K., Carmody, T.J., Kurian, B.T., Webb, C.A., Dillon, D.G., McGrath, P.J., Bruder, G., Fava, M., Parsey, R.V., McInnis, M.G., Adams, P., Trivedi, M.H. (2018). Characterizing anxiety subtypes and the relationship to behavioral phenotyping in major depression: Results from the EMBARC Study. Journal of Psychiatric Research, 102, 207-215. (PDF)

Webb, C.A., Olson, E.A., Killgore, W.D.S., Pizzagalli, D.A., Rauch, S.L., Rosso, I.M. (2018). Rostral anterior cingulate cortex morphology predicts treatment response to internet-based CBT for depression. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 3, 255-262. (PDF)

Webb, C.A., Trivedi, M.D., Cohen, C., Dillon, D.G., Fournier, F., Goer, F., Fava, M., McGrath, P.J., Weissman, M., Parsey, R., Adams, P., Trombello, J.M., Cooper, C., Deldin, P., Oquendo, M.A., McInnis, M.G., Huys, Q., Bruder, G., Kurian, B., Jha, M., DeRubeis, R.J., Pizzagalli D.A. (2018). Personalized prediction of antidepressant versus placebo response: Evidence from the EMBARC trial. Psychological Medicine.  2018 Jul 2:1-10. doi: 10.1017/S0033291718001708. [Epub ahead of print] (PDF)

Whitton, A.E., Deccy, S., Ironside, M.L., Kumar, P., Beltzer, M., Pizzagalli, D.A. (2018). EEG source functional connectivity reveals abnormal high-frequency communication among large-scale functional networks in depression. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 3, 50-58. (PDF)

Whitton, A.E., Mehta, M., Ironside, M.L., Murray, G., Pizzagalli, D.A. (2018). Evidence of a diurnal rhythm in implicit reward learning. Chronobiology International, 35, 1104-1114. (PDF)

Yang J., Zhang, M., Ahn, H., Zhang, Q., Jin, T.B., Li, I.A., Nemesure, M., Joshi, N., Jiang, H., Miller, J.M., Ogden, R.G., Petkova, E., Milak, M.S., Sublette, M.E., Sullivan, G.M., Trivedi, M.H., Weissman, M., McGrath, P.J., Fava, M., Kurian, B.T., Pizzagalli, D.A., Cooper, C.M., McInnis, M., Oquendo, M.A., Mann, J.J., Parsey, R.V., DeLorenzo, C. (2018). Development and evaluation of a multimodal marker of Major Depressive Disorder. Human Brain Mapping, 39, 4420-4439. (PDF)

Pizzagalli Lab (LATN)

2017 Publications

Admon, R.*, Kaiser, R.H.*, Dillon, D.G., Beltzer, M., Goer, F., Olson, D.P., Vitaliano, G., Pizzagalli, D.A. (2017). Dopaminergic enhancement of striatal response to reward in major depression. American Journal of Psychiatry, 174, 378-386. [*Co-first authors] (PDF)

Admon, R.*, Treadway, M.T.*, Valeri, L., Mehta, M., Douglas, S., Pizzagalli, D.A. (2017). Distinct trajectories of cortisol response to prolonged acute stress are linked to affective responses and hippocampal gray matter volume in healthy females. Journal of Neuroscience, 37, 7994-8002. [*Co-first authors] (PDF)

Auerbach, R.P., Pisoni, A., Bondy, E., Kumar, P., Stewart, J.G., Yendiki, A., Pizzagalli, D.A. (2017). Neuroanatomical prediction of anhedonia in adolescents. Neuropsychopharmacology, 42, 2087-2095. (PDF)

Barch, D.M., Carter, C.C., Gold, J.M., Johnson, S.L., Kring, A.M., MacDonald, A.W. III, Pizzagalli, D.A., Ragland, J.D., Silverstein, S.M., Strauss, M.E. (2017). Explicit and implicit reinforcement learning across the psychosis spectrum. Journal of Abnormal Psychology, 26, 694-711. (PDF)

Brennan, B.P, Admon, Perriello, C., LaFlamme, E.M., Athey, A.J., Pizzagalli, D.A., Hudson, J.I., Pope, H.G., Jr., Jensen, J.E. (2017). Acute change in anterior cingulate cortex GABA, but not Glutamine/Glutamate, mediates antidepressant response to citalopram. Psychiatry Research: Neuroimaging, 269, 9-16. (PDF)

Delaparte, L., Yeh, F.C., Adams, P., Malchow, A., Trivedi, M.H., Oquendo, M.A., Deckersbach, T., Ogden, T., Pizzagalli, D.A., Fava, M., Cooper, C., McInnis, M., Kurian, B.T., Weissman, M.M., McGrath, P.J., Klein, D.N., Parsey, R.V., DeLorenzo, C. (2017). A comparison of structural connectivity in anxious depression versus non-anxious depression. Journal of Psychiatric Research, 89, 38-47. (PDF)

Der-Avakian, A., D’Souza, M.S., Potter, D., Chartoff, E.H., Carlezon, W.A. Jr, Pizzagalli, D.A.*, Markou, A.* (2017). Social defeat disrupts reward learning and potentiates striatal nociceptin/orphanin FQ mRNA in rats. Psychopharmacology, 234, 1603-1614. [*These authors made equal senior contributions.] (PDF)

Jensen, J.E.*, Auerbach, R.P.*, Pisoni, A., Pizzagalli, D.A. (2017). Localized MRS reliability of in vivo glutamate at 3 Tesla in shortened scan times: A feasibility study. NMR in Biomedicine, 30, e3771. [*Co-first authors] (PDF)

Pizzagalli, D.A., Carlezon, W.A., Jr. (2017). Error processing in depressive states: A translational opportunity? Neuropsychopharmacology Review, 42, 372. (PDF)

Tenke, C.E., Kayser, J., Pechtel, P., Webb, C.A., Dillon, D.G., Goer, F., Murray, L., Deldin, P., Kurian, B.T., McGrath, P.J., Parsey, R., Trivedi, M., Fava, M., Weissman, M.M., McInnis, M., Abraham, K., Alvarenga, J., Alschuler, D.M., Cooper, C., Pizzagalli, D.A., Bruder, G.E. (2017). Demonstrating test-retest reliability of electrophysiological measures for healthy adults in a multisite study of biomarkers of antidepressant treatment response. Psychophysiology, 54, 34-50. (PDF)

Treadway, M.T., Admon, R., Arulpragasam, A.R., Mehta, M., Douglas, S., Vitaliano, G., Olson, D.P., Cooper, J.A., Pizzagalli, D.A. (2017). Association between interleukin-6 and striatal prediction-error signals following acute stress in healthy female participants. Biological Psychiatry, 82, 570-577. (PDF)

Webb, C.A., Auerbach, R.P., Bondy, E., Stanton, C.H., Foti, D.J., Pizzagalli, D.A. (2017). Abnormal neural responses to feedback in depressed adolescents. Journal of Abnormal Psychology, 126, 19-31. (PDF)

Whitton. A.E., Van’t Veer, A., Kakani, P., Dillon, D.G., Ironside, M.L., Haile, A., Crowley, D.J., Pizzagalli, D.A. (2017). Acute stress impairs frontocingulate activation during error monitoring in remitted depression. Psychoneuroendocrinology, 75, 164-172. (PDF)

Pizzagalli Lab (LATN)

2016 Publications

Auerbach, R. P., Bondy, E., Stanton, C. H., Webb, C. A., Shankman, S. A., & Pizzagalli, D. A. (2016). Self-referential processing in adolescents: Stability of behavioral and event-related potential markers. Psychophysiology, 53, 1398-1406. (PDF)

Auerbach, R.P., Tarlow, N., Bondy, E., Stewart, J.G., Aguirre, B., Kaplan, C., Yang, W., Pizzagalli, D.A. (2016). Electrocortical reactivity during self-referential processing in female youth with Borderline Personality Disorder. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 1, 335-344. (PDF)

Berghorst, L.H.*, Kumar, P.*, Greve, D.N., Deckersbach, T., Ongur, D., Dutra, S.J., Pizzagalli, D.A. (2016). Stress and reward processing in bipolar disorder: a functional magnetic resonance imaging study. Bipolar Disorders, 18, 602-611. [*Co-first authors] (PDF)

Corral-Frías, N.S., Pizzagalli, D.A., Carré, J, Michalski, L.J., Nikolova, Y.S., Perlis, R.H., Fagerness, J., Conley, E.D., Lee, M.R., Lancaster, T.M., Haddad, S., Wolf, A., Hariri, A.R., Smoller, J.W., Bogdan, R. (2016). A common genetic variant in Cathechol-O-methyl-transferase is associated with individual differences in reward-related response bias. Genes, Brain and Behavior, 15, 503-513. (PDF)

Der-Avakian, A., Barnes, S.A., Markou, A., Pizzagalli, D.A. (2016). Translational Assessment of Reward and Motivational Deficits in Psychiatric Disorders. Current Topics in Behavioral Neurosciences, 28, 231-262. (PDF)

Kaiser, R.H., Whitfield-Gabrieli, S., Dillon, D.G., Goer, F., Beltzer, M., Minkel, J., Smoski, M., Dichter, G., Pizzagalli, D.A. (2016). Dynamic resting-state functional connectivity in Major Depression. Neuropsychopharmacology, 41, 1822-1830. (PDF)

Krystal, J.H., … Pizzagalli, D.A., … (2016). Constance E. Lieber, Theodore R. Stanley, and the enduring impact of philanthropy on psychiatry research. Biological Psychiatry, 80, 84-86. [Invited commentary] (42nd author among 64 co-authors ordered alphabetically). (PDF)

Lewandowski, K.E., Whitton, A.E., Pizzagalli, D.A., Norris, L.A., Ongur, D., Hall, M.H. (2016). Reward learning, neurocognition, social cognition, and symptomatology in psychosis. Frontiers in Psychiatry. 7:100.doi: 10.3389/fpsyt.2016.00100. (PDF)

Mueller, E.M., Pizzagalli, D.A. (2016). One year old fear memories rapidly activate human fusiform gyrus. Social Cognitive & Affective Neuroscience, 11, 308-316. (PDF)

Muench, H.M., Westermann, S., Pizzagalli, D.A., Hofmann, S.G., Mueller, E.M. (2016). Self-relevant threat contexts enhance early processing of fear-conditioned faces. Biological Psychology, 121, 194-202. (PDF)

Norton, D.J., McBain, R.K., Pizzagalli, D.A., Cronin-Golomb, A., Chen, Y. (2016). Dysregulation of visual motion inhibition in major depression. Psychiatry Research, 240, 214-221. (PDF)

Pizzagalli, D.A. (2016). Psychobiology of the intersection and divergence of depression and anxiety. Depression and Anxiety, 33, 891-894. (PDF)

Rizvi, S.J., Pizzagalli, D.A., Sproule, B.A., Kennedy, S.H. (2016). Assessing anhedonia in depression: Potentials and pitfalls. Neuroscience & Biobehavioral Reviews, 65, 21-35. (PDF)

Sawyer, A.T., Liverant, G.I., Jun, J.J., Lee, D.J., Cohen, A.L., Dutra, S.J., Pizzagalli, D.A., Sloan, D.M. (2016). Punishment learning in veterans with posttraumatic stress disorder. Journal of Traumatic Stress, 29, 374-378. (PDF)

Trivedi, M.H., McGrath, P.J., Fava, M., Parsey, R.V., Kurian, B.T., Phillips, M.L., Oquendo, M.A., Bruder, G., Pizzagalli, D., Toups, M., Cooper, C., Adams, P., Weyandt, S., Morris, D.W., Grannemann, B., Ogden, R.T., Buckner, R., McInnis, M., Kraemer, H.C., Petkova, E., Carmody, T.J., Weissman, M.M. (2016). Establishing moderators and biosignatures of antidepressant response in clinical care (EMBARC): Rationale and design. Journal of Psychiatric Research, 78, 11-23. (PDF)

Webb, C.A., Dillon, D.G., Pechtel, P., Goer, F., Murray, L., Huys, Q.J.M., Fava, M., McGrath, P.J., Weissman, M., Parsey, R., Kurian, B., Adams, P., Weyandt, S., Trombello, J., Grannemann, B., Cooper, C., Deldin, P., Tenke, C., Trivedi, M., Bruder, G., Pizzagalli, D.A. (2016). Neural correlates of three promising endophenotypes of depression: Evidence from the EMBARC study. Neuropsychopharmacology, 41, 454-463. (PDF)

Whitton, A.E., Kakani, P., Foti, D., Van’t Veer, A., Haile, A., Crowley, D.J., Pizzagalli, D.A. (2016). Blunted neural responses to reward in remitted Major Depression: A high-density event-related potential study. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging, 1, 87-95. (PDF)

2015 Publications

Abramovitch, A., Pizzagalli, D.A., Geller, D.A., Reuman, L., Wilhelm, S. (2015). Cigarette smoking in obsessive-compulsive disorder and unaffected parents of OCD patients. European Psychiatry, 30, 137-144. (PDF)

Admon, R., Holsen, L.M., Aizley, H., Remington, A., Whitfield-Gabrieli, S., Goldstein, J.M., Pizzagalli, D.A. (2015). Striatal hyper-sensitivity during stress in remitted individuals with recurrent depression. Biological Psychiatry, 78, 67-76. (PDF)

Admon, R., Nickerson, L.D., Dillon, D.G., Holmes, A.J., Bogdan, R., Kumar, P., Dougherty, D.D., Iosifescu, D.V., Mischoulon, D., Fava, M., Pizzagalli, D.A. (2015). Dissociable cortico-striatal connectivity abnormalities in major depression in response to monetary gains and penalties. Psychological Medicine, 45, 121-31. (PDF)

Admon, R., Pizzagalli, D.A. (2015). Corticostriatal pathways contribute to the natural time course of positive mood. Nature Communications. 6:10065 doi: 10.1038/ncomms10065. (PDF)

Admon, R., Pizzagalli, D.A. (2015). Dysfunctional reward processing in depression. Current Opinion in Psychology, 4, 114-118. (PDF)

Auerbach, R.P., Stanton, C.H., Proudfit, G.H., Pizzagalli, D.A. (2015). Self-referential processing in adolescent depression: A high-density ERP study. Journal of Abnormal Psychology, 124, 233-245. (PDF)

Beard, C., Donahue, R.J., Dillon, D.G., Van’t Veer, A., Webber, C., Lee, J., Barrick, E., Hsu, K.J., Foti, D., Carroll, F.Y, Carlezon, W.A., Jr., Björgvinsson, T., Pizzagalli, D.A. (2015). Abnormal error processing in depressive states: A Translational examination in humans and rats. Translational Psychiatry. (2015) 5, e564; doi:10.1038/tp.2015.54 (PDF)

Dillon, D.G.*, Wiecki, T.*, Pechtel, P., Webb, C., Goer, F., Murray, L., Trivedi, M., Fava, M., McGrath, P.J., Weissman, M., Parsey, R., Kurian, B., Adams, P., Carmody, T., Weyandt, S., Shores-Wilson, K., Toups, M., McInnis, M., Oquendo, M.A., Cusin, C., Deldin, P., Bruder, G., Pizzagalli, D.A. (2015). A computational analysis of Flanker interference in depression. Psychological Medicine, 45, 2333-2344. [*These authors made equal contributions.] (PDF)

Fletcher, K., Parker, G., Paterson, A., Fava M., Iosifescu, D., Pizzagalli, D.A. (2015). Anhedonia in melancholic and non-melancholic depressive disorders. Journal of Affective Disorders, 184, 81-88. (PDF)

Hsu, K.J., Beard, C., Rifkin, L., Dillon, D.G., Pizzagalli, D.A., Björgvinsson, T. (2015). Transdiagnostic mechanisms in depression and anxiety: The role of rumination and attentional control. Journal of Affective Disorders, 188, 22-27. (PDF)

Janes, A.C.*, Pedrelli, P.*, Whitton, A.E., Pechtel, P., Douglas, S., Martinson, M.A., Huz, I., Fava, M., Pizzagalli, D.A.**, Evins, A.E.** (2015). Reward responsiveness varies by smoking status in women with a history of major depressive disorder. Neuropsychopharmacology, 40, 1940-1946 [*These authors made equal contributions; **These authors made equal senior contributions.] (PDF)

Kaiser R.H., Andrews-Hanna J.R., Wager T.D., Pizzagalli D.A. (2015). Large-Scale Network Dysfunction in Major Depressive Disorder: A Meta-analysis of Resting-State Functional Connectivity. JAMA Psychiatry, 72, 603-611. (PDF)

Kaiser, R.H, Pizzagalli, D.A. (2015). Dysfunctional connectivity in the depressed adolescent brain. Biological Psychiatry, 78, 594-595. (PDF)

Kumar, P., Slavich, G.M., Berghorst, L.H., Treadway, M.T., Brooks, N.H., Dutra, S.J., Greve, D.N., O’Donovan, A., Bleil, M.E., Maninger, N., Pizzagalli, D.A. (2015). Perceived chronic stress exposure modulates reward-related medial prefrontal cortex responses to acute stress in depression. Journal of Affective Disorders, 180, 104-111. (PDF)

Mueller, E.M., Panitz, C., Pizzagalli, D.A., Hermann, C., Wacker, J. (2015). Midline theta dissociates agentic extraversion and anhedonic depression. Personality and Individual Differences, 79, 172-177. (PDF)

Mueller, E.M., Pechtel, P., Cohen, A.L., Douglas, S.R., Pizzagalli, D.A. (2015). Potentiated processing of negative feedback in depression is attenuated by anhedonia. Depression and Anxiety, 32, 296-305. (PDF)

Peechatka, A.L., Whitton, A.E., Farmer, S.L., Pizzagalli, D.A., Janes, A.C. (2015). Cigarette craving is associated with blunted reward processing in nicotine-dependent smokers. Drug and Alcohol Dependence, 155, 202-207. (PDF)

Treadway, M.T., Waskom, M.L., Dillon, D.G., Holmes, A.J., Park, M.T.M., Chakravarty, M.M., Dutra, S.J., Polli, F.E., Iosifescu, D.V., Fava, M., Gabrieli, J.D.E., Pizzagalli, D.A. (2015). Illness progression, recent stress and morphometry of hippocampal subfields and medial prefrontal cortex in Major Depression. Biological Psychiatry, 77, 285-294. (PDF)

Whitton, A.E., Treadway, M.T, Pizzagalli, D.A. (2015). Reward processing dysfunction in major depression, bipolar disorder and schizophrenia. Current Opinion in Psychiatry, 28, 7-12. (PDF)

Pizzagalli Lab (LATN)

2014 Publications

Abramovitch, A., Reuman, L., Pizzagalli, D.A., Wilhelm, S. (2014). Anhedonia in Obsessive-Compulsive Disorder: Beyond comorbid depression. Psychiatry Research, 216, 223-229. (PDF)

Auerbach, R.P., Admon, R., Pizzagalli, D.A. (2014). Adolescent depression: Stress and reward dysfunction. Harvard Review of Psychiatry, 22, 139-148. (PDF)

Chumbley, J.R, Hulme, O., Köchli, H., Russell E., Van Uum, S., Pizzagalli D.A., Fehr, E. (2014). Stress and reward: Long term cortisol exposure predicts the strength of sexual preference. Physiology & Behavior, 131, 33-40. (PDF)

Dillon, D.G., Dobbins, I.G., Pizzagalli, D.A. (2014). Weak reward source memory in depression reflects blunted activation of VTA/SN and parahippocampus. Social Cognitive and Affective Neuroscience, 9, 1576-1583. (PDF)

Dillon, D. G., Rosso, I. M., Pechtel, P., Killgore, W. D. S., Rauch, S. L., Pizzagalli, D.A. (2014). Peril and pleasure: an RDoC-inspired examination of threat responses and reward processing in anxiety and depression. Depression and Anxiety, 31, 233-249. (PDF)

Kumar, P., Berghorst, L.H., Nickerson, L.D., Dutra, S.J., Goer, F., Greve, D., Pizzagalli, D.A. (2014). Differential effects of acute stress on anticipatory and consummatory phases of reward processing. Neuroscience, 266, 1-12. (PDF)

Liverant, G.I., Sloan, D.M., Pizzagalli, D.A., Harte, C.B., Kamholz, B.W., Rosebrock, L.E., Cohen, A.L., Fava, M., Kaplan, G.B. (2014). Associations among smoking, anhedonia, and reward learning in depression. Behavior Therapy, 45, 651-663. (PDF)

Mueller, E.M., Panitz, C., Hermann, C., Pizzagalli, D.A. (2014). Prefrontal oscillations during recall of conditioned and extinguished fear in humans. Journal of Neuroscience, 34, 7059-66. (PDF)

Pergadia, M.L., Der-Avakian, A., D’Souza, M.S., Madden, P.A.F., Heath, A.C., Shiffman, S., Markou, A., Pizzagalli, D.A. (2014). Withdrawal of nicotine blunts reward responsiveness in humans and rats. JAMA Psychiatry, 71, 1238-1245. (PDF)

Pizzagalli, D.A. (2014). Depression, stress, and anhedonia: Toward a synthesis and integrated model. Annual Review of Clinical Psychology, 10, 393-423. (PDF)

Treadway, M.T., Pizzagalli, D.A. (2014). Imaging the pathophysiology of Major Depressive Disorder – From localist models to circuit-based analysis. Biology of Mood & Anxiety Disorders. 2014 4:5. (PDF)

Vrieze, E., Demyttenaere, K., Bruffaerts, R., Hermans, D., Pizzagalli, D.A., Sienaert, P., Hompes, T., de Boer, P., Schmidt, M., Claes S. (2014). Dimensions in major depressive disorder and their relevance for treatment outcome. Journal of Affective Disorders, 155, 35-41. (PDF)

Pizzagalli Lab (LATN)

2013 Publications

Berghorst, L.H., Bogdan, R., Frank, M.J., Pizzagalli, D.A. (2013). Acute stress selectively reduces reward sensitivity Frontiers in Human Neuroscience 7:133. doi:10.3389/fnhum.2013.00133. (PDF)

Bogdan R., Nikolova, Y.S., Pizzagalli, D.A. (2013). Neurogenetics of depression: A focus on reward processing and stress sensitivity. Neurobiology of Disease, 52, 12-23. (PDF)

Der-Avakian, A., D’Souza, M.S., Pizzagalli, D.A.*, Markou, A.* (2013). Assessment of reward responsiveness in the Response Bias Probabilistic Reward Task in rats: Implications for cross-species translational research. Translational Psychiatry 3, e297; doi:10.1038/tp.2013.74 [*Contributed equally as senior authors]. (PDF)

Dillon, D.G., Pizzagalli, D.A. (2013). Evidence of successful modulation of brain activation and subjective experience during reappraisal of negative emotion in unmedicated depression. Psychiatry Research: Neuroimaging, 212, 99-107. (PDF)

Goetz, E.L., Hariri, A.R., Pizzagalli, D.A., Strauman, T.J. (2013). Genetic moderation of the association between regulatory focus and reward responsiveness: A proof-of-concept study. Biology of Mood & Anxiety Disorders. 2013 Feb 1;3(1):3. doi: 10.1186/2045-5380-3-3. (PDF)

Huys, Q.J.M, Pizzagalli, D.A., Bogdan, R., Dayan, P. (2013). Mapping anhedonia onto reinforcement learning: A behavioural meta-analysis. Biology of Mood & Anxiety Disorders. 2013, 3:12. (PDF)

Janes, A.C., Jensen, J.E., Farmer, S.L., Frederick, B.D., Pizzagalli, D.A., Lukas, S.E. (2013). GABA levels in the dorsal anterior cingulate cortex associated with difficulty ignoring smoking-related cues in tobacco-dependent volunteers. Neuropsychopharmacology, 38, 1113-1120. (PDF)

Pechtel, P., Dutra, S.J., Goetz, E.L., Pizzagalli, D.A. (2013). Blunted reward responsiveness in remitted depression. Journal of Psychiatric Research, 47, 1864-1869. (PDF)

Pechtel, P., Pizzagalli, D.A. (2013). Disrupted reinforcement learning and maladaptive behavior in women with a history of childhood sexual abuse: A high-density event-related potential study. JAMA Psychiatry, 70, 499-507. (PDF)

Vrieze, E., Ceccarini, J., Pizzagalli, D.A., Bormans, G., Vandenbulcke, M., Demyttenaere, K., Van Laere, K., Claes S. (2013). Measuring extrastriatal dopamine release during a reward learning task. Human Brain Mapping, 34, 575-586. (PDF)

Vrieze, E., Pizzagalli, D.A., Demyttenaere, K., Hompes, T., Sienaert, P., de Boer, P., Schmidt, M., Claes S. (2013). Reduced reward learning predicts outcome in Major Depressive Disorder. Biological Psychiatry, 73, 639-645. (PDF)

Wacker, J., Mueller, E.M., Pizzagalli, D.A., Hennig, J., Stemmler, G. (2013). Dopamine-D2-receptor blockade reverses the association between trait approach motivation and frontal asymmetry in an approach-motivation context. Psychological Science, 24, 489-497. (PDF)

Pizzagalli Lab (LATN)

2012 Publications

AhnAllen, C.G., Liverant, G.I., Gregor, K.L., Kamholz, B.W., Levitt, J., Gulliver, S.B., Pizzagalli, D.A., Koneru, V., Kaplan, G. (2012). The relationship between reward-based learning and nicotine dependence in smokers with schizophrenia. Psychiatry Research, 196, 9-14. (PDF)

Bogdan, R., Pringle, P., Goetz, E.L., Pizzagalli, D.A. (2012). Perceived stress, anhedonia and illusion of control: Evidence for two meditational models. Cognitive Therapy and Research, 36, 827-832. (PDF)

Dutra, S.J., Stoeckel, L.E., Carlini, S.V., Pizzagalli, D.A.*, Evins, A.E.* (2012). Varenicline as a smoking cessation aid in schizophrenia: Effects on smoking behavior and reward sensitivity. Psychopharmacology, 219, 25-34 [*Contributed equally as senior authors]. (PDF)

Grob, S., Pizzagalli, D.A., Dutra, S.J., Stern, J., Mörgeli, H., Milos, G., Schnyder, U., Hasler, G. (2012). Dopamine-related deficit in reward learning after catecholamine depletion in unmedicated, remitted subjects with Bulimia Nervosa. Neuropsychopharmacology, 37, 1945-1952. (PDF)

Millner, A.J., Jaroszewski, A.C., Chamarthi, H., Pizzagalli, D.A. (2012). Behavioral and electrophysiological correlates of training-induced cognitive control improvements. NeuroImage, 63, 742-753. (PDF)

Nikolova, Y., Bogdan, R., Pizzagalli, D.A. (2012). Perception of a naturalistic stressor interacts with 5-HTTLPR genotype and gender to impact reward responsiveness. Neuropsychobiology, 65, 45-54. (PDF)

Santesso, D.L., Bogdan, R., Birk, J.L., Goetz, E.L., Holmes, A.J., Pizzagalli, D.A. (2012). Neural responses to negative feedback are related to negative emotionality in healthy adults. Social Cognitive and Affective Neuroscience, 7, 794-803. (PDF)

Vanderhasselt, M.A., De Raedt, R., Dillon, D.G., Dutra, S.J., Brooks, N., Pizzagalli, D.A. (2012). Decreased cognitive control in response to negative information in remitted depression: An Event Related Potential study. Journal of Psychiatry and Neuroscience, 37, 250-258. (PDF)

Pizzagalli Lab (LATN)

2011 Publications

Bogdan, R., Santesso, D.L., Fagerness, J., Perlis, R.H., Pizzagalli, D.A. (2011). Corticotropin-releasing hormone receptor type 1 (CRHR1) genetic variation and stress interact to influence reward learning. Journal of Neuroscience, 31, 13246-13254. (PDF)

Denninger, J.W., van Nieuwenhuizen, A.O, Wisniewski, S.R., Luther, J.F., Trivedi, M.H., Rush, A.J., Gollan, J.K., Pizzagalli, D.A., Fava, M. (2011). Changes in depressive symptoms and social functioning in STAR*D. Journal of Nervous and Mental Disease, 199, 807-810. (PDF)

Dillon, D.G., Deveney, C.M., Pizzagalli, D.A. (2011). From basic processes to real-world problems: How research on emotion and emotion regulation can inform understanding of psychopathology, and vice versa. Emotion Review, 3, 74–82. (PDF)

Koslov, K., Mendes, W.B., Pajtas, P.E., Pizzagalli, D.A. (2011). Asymmetry in resting intracortical activity as a buffer to social threat. Psychological Science, 22, 641-649. (PDF)

Pechtel, P., Pizzagalli, D.A. (2011). Effects of early life stress on cognitive and affective function: An integrated review of human literature. Psychopharmacology, 214, 55-70. (PDF)

Pizzagalli, D.A. (2011). Frontocingulate dysfunction in depression: Towards biomarkers of treatment response. Neuropsychopharmacology Review, 36, 183-206. (PDF)

Pizzagalli Lab (LATN)

2010 Publications

Bogdan, R., Perlis, R.H., Fagerness, J., Pizzagalli, D.A. (2010). The impact of Mineralocorticoid Receptor ISO/VAL genotype (rs5522) and stress on reward learning. Genes, Brain and Behavior, 9, 658-667. (PDF)

Dillon, D.G., Bogdan, R., Fagerness, J., Holmes, A.J., Perlis, R.H., Pizzagalli, D.A. (2010). Variation in TREK1 gene linked to depression-resistant phenotype is associated with potentiated neural responses to rewards in humans. Human Brain Mapping, 31, 210-221. (PDF)

Holmes, A.J., Bogdan, R., Pizzagalli, D.A. (2010). Serotonin transporter genotype and action monitoring dysfunction: A possible substrate underlying increased vulnerability to depression. Neuropsychopharmacology, 35, 1186-1197. (PDF)

Holmes, A.J., Pizzagalli, D.A. (2010). Effects of task-relevant incentives on the electrophysiological correlates of error processing in Major Depressive Disorder. Cognitive, Affective, and Behavioral Neuroscience, 10, 119-128. (PDF)

Janes, A.C., Pizzagalli, D.A., Richardt, S., Frederick, B.D., Chuzi, S., Pachas, G., Culhane, M.A., Holmes, A.J., Fava, M., Evins, A.E., Kaufman, M.J. (2010). Brain reactivity to smoking cues prior to smoking cessation predicts ability to maintain tobacco abstinence. Biological Psychiatry, 67, 722-729. (PDF)

Janes, A.C., Pizzagalli, D.A., Richardt, S., Frederick, B.B., Holmes, A.J., Sousa, J., Fava, M., Evins, A.E., Kaufman, M.J. (2010). Neural substrates of attentional bias for smoking-related cues: an fMRI study. Neuropsychopharmacology, 35, 2339-2345. (PDF)

Lempert, K.M., Pizzagalli, D.A. (2010). Delay discounting and future-directed thinking in anhedonic individuals. Journal of Behavior Therapy and Experimental Psychiatry,41, 258-264. (PDF)

Pizzagalli, D.A. (2010). The “anhedonia paradox” in schizophrenia: Insights from affective neuroscience. Biological Psychiatry, 67, 899-901. PDF

Pizzagalli Lab (LATN)

2009 Publications

Bogdan, R., Pizzagalli, D.A. (2009). The heritability of hedonic capacity and perceived stress: A twin study evaluation of candidate depressive phenotypes. Psychological Medicine, 39, 211-218. (PDF)

Dillon, D.G., Holmes, A.J., Birk, J.L., Brooks, N., Lyons-Ruth, K., Pizzagalli, D.A. (2009). Childhood adversity is associated with left basal ganglia dysfunction during reward anticipation in adulthood. Biological Psychiatry, 66, 206-213. (PDF)

Mueller, E.M., Hofmann, S.G., Santesso, D.L., Meuret, A.E., Bitran, S., Pizzagalli, D.A. (2009). Electrophysiological evidence of attentional biases in Social Anxiety Disorder. Psychological Medicine, 39, 1141-1152. (PDF)

Pizzagalli, D.A., Holmes, A.J., Dillon, D.G., Goetz, E.L., Birk, J.L., Bogdan, R., Dougherty, D.D., Iosifescu, D.V., Rauch, S.L., Fava, M. (2009). Reduced caudate and nucleus accumbens response to rewards in unmedicated subjects with Major Depressive Disorder. American Journal of Psychiatry, 166, 702-710. (PDF)

Ragland, J.D., Cools, R.*, Frank, M.*, Pizzagalli, D.A.*, Preston, A.*, Ranganatht, C.*, Wagner, A.D.* (2009). CNTRICS final task selection: Long-term memory. Schizophrenia Bulletin, 35, 197-212. [*co-authors had equivalent input and are listed in alphabetical order.] (PDF)

Santesso, D.L., Evins, A.E., Frank, M.J., Schetter, E.C., Pizzagalli, D.A. (2009). Single dose of a dopamine agonist impairs reinforcement learning in humans: Evidence from event-related potentials and computational modeling of striatal-cortical function. Human Brain Mapping, 30, 1963-1976. (PDF)

Wacker, J., Dillon, D.G., Pizzagalli, D.A. (2009). The role of the nucleus accumbens and rostral anterior cingulate cortex in anhedonia: Integration of resting EEG, fMRI, and volumetric techniques. NeuroImage, 46, 327-337. (PDF)

Pizzagalli Lab (LATN)

2008 Publications

Barr, R.S., Pizzagalli, D.A., Culhane, M.A, Goff, D.C., Evins, A.E. (2008). A single dose of nicotine enhances reward responsiveness in non-smokers: Implications for development of dependence. Biological Psychiatry, 63, 1061-1065. (PDF)

Chiu, P.H., Holmes, A.J., Pizzagalli, D.A. (2008). Dissociable recruitment of rostral anterior cingulate and inferior frontal cortex in emotional response inhibition. NeuroImage, 42, 988-997. (PDF)

Deveney, C.M., Pizzagalli, D.A. (2008). The cognitive consequences of emotion regulation: An ERP investigation. Psychophysiology, 45, 435-444. (PDF)

Dillon, D.G., Holmes, A.J., Jahn, A.L., Bogdan, R., Wald, L.L., Pizzagalli, D.A. (2008). Dissociation of neural regions associated with anticipatory versus consummatory phases of incentive processing. Psychophysiology, 45, 36-49. (PDF)

Holmes, A.J., Pizzagalli, D.A. (2008). Response conflict and frontocingulate dysfunction in unmedicated participants with Major Depression. Neuropsychologia, 46, 2904-2913. (PDF)

Holmes, A.J., Pizzagalli, D.A. (2008). Spatio-temporal dynamics of error processing dysfunctions in Major Depressive Disorder. Archives of General Psychiatry, 65, 179-188. (PDF)

Meites, T.M., Deveney, C.M., Steele, K.T., Holmes, A.J., Pizzagalli, D.A. (2008). Implicit depression and hopelessness in remitted depressed individuals. Behaviour Research and Therapy, 46, 1078-1084. (PDF)

Pizzagalli, D.A., Evins, A.E., Schetter, E.C., Frank, M.J., Pajtas, P.E., Santesso, D.L., Culhane, M. (2008). Single dose of a dopamine agonist impairs reinforcement learning in humans: Behavioral evidence from a laboratory-based measure of reward responsiveness. Psychopharmacology, 196, 221-232. (PDF)

Pizzagalli, D.A., Goetz, E., Ostacher, M., Iosifescu, D.V., Perlis, R.H. (2008). Euthymic patients with Bipolar Disorder show decreased reward learning in a probabilistic reward task. Biological Psychiatry, 64, 162-168. (PDF)

Pizzagalli, D.A., Iosifescu, D., Hallett, L.A., Ratner, K.G., Fava, M. (2008). Reduced hedonic capacity in Major Depressive Disorder: Evidence from a probabilistic reward task. Journal of Psychiatric Research, 43, 76-87. (PDF)

Putnam, K.M., Pizzagalli, D.A., Gooding, D.C., Kalin, N.H., Davidson, R.J. (2008). Neural activity and diurnal variation of cortisol: Evidence from brain electrical tomography analysis and relevance to anhedonia. Psychophysiology, 45, 886-895. (PDF)

Santesso, D.L., Dillon, D.G., Birk, J.L., Holmes, A.J., Goetz, E., Bogdan, R., Pizzagalli, D.A. (2008). Individual differences in reinforcement learning: Behavioral, electrophysiological, and neuroimaging correlates. NeuroImage, 42, 807-816. (PDF)

Santesso, D.L., Meuret, A.E., Hofmann, S.G., Mueller, E.M., Ratner, K.G., Roesch, E.B., Pizzagalli, D.A. (2008). Electrophysiological correlates of spatial orienting towards angry faces: A source localization study. Neuropsychologia, 46, 1338-1348. (PDF)

Santesso, D.L, Steele, K.T., Bogdan, R., Holmes, A.J., Deveney, C.M., Meites, T.M., Pizzagalli, D.A. (2008). Enhanced negative feedback responses in remitted depression. NeuroReport, 19, 1045-1048. (PDF)

Pizzagalli Lab (LATN)

2007 Publications

Candrian, M., Farabaugh, A., Pizzagalli, D.A., Baer, L., Fava, M. (2007). Perceived stress and cognitive vulnerability mediate the effects of Personality Disorder comorbidity on treatment outcome in Major Depressive Disorder: A path analysis study. Journal of Nervous and Mental Disease, 195, 729-737. (PDF)

Dillon, D.G., Pizzagalli, D.A. (2007). Inhibition of action, thought, and emotion: A selective neurobiological review. Applied & Preventive Psychology, 12, 99-114. (PDF)

Holmes, A.J., Pizzagalli, D.A. (2007) Task feedback effects on conflict monitoring and executive control: Relationship to subclinical measures of depression. Emotion, 7, 68-76. (PDF)

Pizzagalli, D.A., Bogdan, R., Ratner, K.G., Jahn, A.L. (2007). Increased perceived stress is associated with blunted hedonic capacity: Potential implications for depression research. Behaviour Research and Therapy, 45, 2742-2753. (PDF)

Pizzagalli Lab (LATN)

2004-2006 Publications

Bogdan, R., Pizzagalli, D.A. (2006). Acute stress reduces reward responsiveness: Implications for depression. Biological Psychiatry, 60, 1147-1154. (PDF)

Pizzagalli, D.A., Peccoralo, L.A., Davidson, R.J., Cohen, J.D. (2006). Resting anterior cingulate activity and abnormal responses to errors in subjects with elevated depressive symptoms: A 128-channel EEG study. Human Brain Mapping, 27, 185-201. (PDF)

Shackman, A.J., Sarinopoulos, I., Maxwell, J.S., Pizzagalli, D.A., Lavric, A., Davidson, R.J. (2006). Anxiety selectively disrupts visuospatial working memory. Emotion, 6, 40-61. (PDF)

Hofmann, S.G., Moscovitch, D.A, Litz, B.T., Kim, H.-J., Davis, L.L., Pizzagalli, D.A. (2005). The worried mind: Autonomic arousal and prefrontal activation during worrying. Emotion, 5, 464-475. (PDF)

Pizzagalli, D.A. (2005). The role of frontocingulate pathways in the emotion-cognition interface: Emerging clues from depression. [Invited commentary] Behavioral and Brain Sciences, 28, 214-215. (PDF)

Pizzagalli, D.A., Deveney, C.M. (2005). Impaired hedonic capacity in major depressive disorder: Impact on affiliative behaviors. [Invited commentary] Behavioral and Brain Sciences, 28, 362-363. (PDF)

Pizzagalli, D.A., Jahn, A.L., O’Shea, J.P. (2005). Toward an objective characterization of an anhedonic phenotype: A Signal-detection approach. Biological Psychiatry, 57, 319-327. (PDF)

Pizzagalli, D.A., Sherwood, R.J., Henriques, J.B., Davidson, R.J. (2005). Frontal brain asymmetry and reward responsiveness: A Source localization study. Psychological Science, 16, 805-813. (PDF)

Lavric, A., Pizzagalli, D.A., Forstmeier, S. (2004). When ‘go’ and ‘nogo’ are equally frequent: ERP components and cortical tomography. European Journal of Neuroscience, 20, 2483-2488. (PDF)

Pizzagalli, D.A., Oakes, T.R., Fox, A.S., Chung, M.K., Larson, C.L., Abercrombie, H.C., Schaefer, S.M., Benca, R.M., Davidson, R.J. (2004). Functional but not structural subgenual prefrontal cortex abnormalities in melancholia. Molecular Psychiatry, 9, 393-405. (PDF)

Oakes, T.R., Pizzagalli, D.A., Hendrick, A.M., Horras, K.A., Larson, C.L., Abercrombie, H.C., Schaefer, S.M., Koger, J.V., Davidson, R.J. (2004). Functional coupling of simultaneous electrical and metabolic activity in the human brain. Human Brain Mapping, 21, 257-270. (PDF)

Greischar, L.L., Burghy, C.A., Van Reekum, C.M., Jackson, D.C., Pizzagalli, D.A., Mueller, C., Davidson, R.J (2004). Effects of electrode density and electrolyte spreading in dense array electroencephalographic recording. Clinical Neurophysiology, 115, 710-720. (PDF)

Pizzagalli Lab (LATN)

2001-2003 Publications

Pizzagalli, D.A., Greischar, L.L., Davidson, R.J. (2003). Spatio-temporal dynamics of brain mechanisms in aversive classical conditioning: High-density event-related potential and brain electrical tomography analyses. Neuropsychologia, 41, 184-194. (PDF)

Pizzagalli, D.A., Oakes, T.R., & Davidson, R.J. (2003). Coupling of theta activity and glucose metabolism in the human rostral anterior cingulate cortex: An EEG/PET study of normal and depressed subjects. Psychophysiology, 40, 939-949. (PDF)

Davidson, R.J., Pizzagalli, D., Nitschke, J.B., Putman, K. (2002). Depression: Perspectives from affective neuroscience. Annual Review of Psychology, 53, 545-574. (PDF)

Pizzagalli, D.A., Lehmann, D., Hendrick, A.M., Regard, M., Pascual-Marqui, R.D., Davidson, R.J. (2002). Affective judgments of faces modulate early activity (~160 ms) within the fusiform gyri. NeuroImage, 16, 663-677. PDF

Pizzagalli, D.A., Nitschke, J.B., Oakes, T.R., Hendrick, A.M., Horras, K.A., Larson, C.L., Abercrombie, H.C., Schaefer, S.M., Koger, J.V., Benca, R.M., Pascual-Marqui, R.D., Davidson, R.J. (2002). Brain electrical tomography in depression: The importance of symptom severity, anxiety, and melancholic features. Biological Psychiatry, 52, 73-85. (PDF)

Silva, J.R., Pizzagalli, D.A., Larson, C.L., Jackson, D.C., Davidson, R.J. (2002). Frontal brain asymmetry in restrained eaters. Journal of Abnormal Psychology, 111, 676-681. (PDF)

Gianotti, L.L.R., Mohr, C., Pizzagalli, D., Lehmann, D., Brugger, P. (2001). Associative processing and paranormal belief. Psychiatry and Clinical Neurosciences, 55, 595-603. (PDF)

Lavric, A., Pizzagalli, D., Forstmeier, S., Rippon, G. (2001). Mapping dissociations in verb morphology. Trends in Cognitive Sciences, 5, 301-308. (PDF)

Lavric, A., Pizzagalli, D., Forstmeier, S., Rippon, G. (2001). A double-dissociation of English past-tense production revealed by event-related potentials and low resolution electromagnetic tomography (LORETA). Clinical Neurophysiology, 112, 1833-1849. (PDF)

Lehmann, D., Faber, P.L., Achermann, P., Jeanmonod, D., Gianotti, L.R.R., Pizzagalli, D. (2001). Brain sources of EEG gamma frequency during volitionally meditation-induced, altered states of consciousness, and experience of the self. Psychiatry Research: Neuroimaging, 108, 111-121. (PDF)

Mohr, C., Graves, R.E., Gianotti, L., Pizzagalli, D., Brugger, P. (2001). Loose but normal: A semantic association study. Journal of Psycholinguistic Research, 30, 475-483. (PDF)

Pizzagalli, D., Lehmann, D., Brugger, P. (2001). Lateralized direct and indirect semantic priming effects in subjects with paranormal experiences and beliefs. Psychopathology, 34, 75-80. (PDF)

Pizzagalli, D., Pascual-Marqui, R.D., Nitschke, J.B., Oakes, T.R., Larson, C.L., Abercrombie, H.C., Schaefer, S.M., Koger, J.V., Benca, R.M., Davidson, R.J. (2001). Anterior cingulate activity as a predictor of degree of treatment response in major depression: Evidence from brain electrical tomography analysis. American Journal of Psychiatry, 158, 405-415. (PDF)

Pizzagalli Lab (LATN)

1998-2000 Publications

Pizzagalli, D., Lehmann, D., Gianotti, L., Koenig, T., Tanaka, H., Wackermann, J., Brugger, P. (2000). Brain electric correlates of strong belief in paranormal phenomena: Intracerebral EEG source and regional Omega complexity analyses. Psychiatry Research: Neuroimaging, 100, 139-154. (PDF)

Pizzagalli, D., Lehmann, D., Koenig, T., Regard, M., Pascual-Marqui, R.D. (2000). Face-elicited ERPs and affective attitude: Brain electric microstate and tomography analyses. Clinical Neurophysiology, 111, 521-531. (PDF)

Pizzagalli, D., Koenig, T., Regard, M., Lehmann, D. (1999). Affective attitudes to face images associated with intracerebral EEG source location before face viewing. Cognitive Brain Research, 7, 371-377. (PDF)

Pizzagalli, D., Regard, M., & Lehmann, D. (1999). Rapid emotional face processing in the human right and left brain hemispheres. NeuroReport, 10, 2691-2698. (PDF)

Pizzagalli, D., Koenig, T., Regard, M., Lehmann, D. (1998). Faces and emotions: Brain electric field sources during covert emotional processing. Neuropsychologia, 36, 323-332. (PDF)

Pizzagalli Lab (LATN)

Book Chapters

Berghorst, L., Pizzagalli, D.A. (2010). Defining depression endophenotypes. In C.E. Beyer and S.A. Stahl (Eds.), Next Generation Antidepressants. Moving Beyond Monoamines To Discover Novel And Differentiated Treatment Strategies For Mood Disorders. Cambridge University Press, pp. 70-89. (PDF)

Davidson, R.J., Pizzagalli, D., Nitschke, J.B. (2009). The representation and regulation of emotion in depression: Perspectives from affective neuroscience. In: I. Gotlib and C. Hammen (Eds.), Handbook of Depression (2nd edition). New York: Guilford Press, pp. 218-248.

Davidson, R.J., Pizzagalli, D., Nitschke, J.B. (2002). The representation and regulation of emotion in depression: Perspectives from affective neuroscience. In: I. Gotlib and C. Hammen (Eds.), Handbook of Depression. New York: Guilford Press, pp. 219-244.

Davidson, R.J., Pizzagalli, D., Nitschke, J.B., Kalin, N.H. (2003). Parsing the subcomponents of emotion and disorders of emotion: Perspectives from affective neuroscience. In: R.J. Davidson, K.R. Scherer, H.H., Goldsmith (Eds.), The Handbook of Affective Science. Oxford: University Press, pp. 8-24.

Dillon, D. G., Pizzagalli, D.A. (2010). Maximizing positive emotions: A translational, transdiagnostic look at positive emotion regulation. In: A. M Kring and D. M. Sloan (Eds.), Emotion Regulation and Psychopathology, Guilford Press, New York, pp. 229-252.

Lehmann, D., Koenig, T., Pizzagalli, D. (1999). Gedanken und Emotionen im elektrischen Feld des Hirns. In: W. Machleidt, H. Haltenhof und P. Garlipp (Eds.), Schizophrenie – eine affektive Erkrankung? Stuttgart: Schattauer, pp. 31-43.

Pizzagalli, D.A., Dillon, D.G., Bogdan, R., Holmes, A. (2011). Reward and punishment processing in the human brain: Clues from affective neuroscience and implications for depression research. In: O. Vartanian and D. Mandel (Eds.), Neuroscience of Decision Making. New York: Psychology Press, pp. 199-220.

Pizzagalli, D.A. (2009). Anhedonia. In: D. Sander and K.R. Scherer (Eds.), The Oxford Companion to Emotion and the Affective Sciences. New York: Oxford University Pres, p. 33.

Pizzagalli, D.A. (2007). Electroencephalography and High-Density Electrophysiological Source Localization. In: J.T. Cacioppo, L.G. Tassinary, G.G. Berntson (Eds.), Handbook of Psychophysiology (3rd Edition). Cambridge, U.K.: Cambridge University Press, pp. 56-84. PDF

Pizzagalli, D.A., Dillon, D. G., Bogdan, R., Holmes, A. (in press). Reward and Punishment Processing in the Human Brain: Clues from Affective Neuroscience and Implications for Depression Research. In: O. Vartanian and D. Mandel (Eds.), Neuroscience of Decision Making. Psychology Press, pp. 199-220.

Pizzagalli, D., Hendrick, A.M., Horras, K.A., Davidson, R.J. (2002). Anterior cingulate theta activity is associated with degree of treatment response in major depression. In: K. Hirata, Y. Koga, K. Nagata, K. Yamazaki (Eds.), Recent Advances in Human Brain Mapping. Proceedings of the 12th World Congress of the International Society for Brain Electromagnetic Topography (ISBET 2001). Excerpta Medica, International Congress Series 1232. Amsterdam: Elsevier Science B.V., pp. 711-7.

Pizzagalli, D., Lehmann, D., Koenig, T., Regard, M., Pascual-Marqui, R. D. (2002). Face-elicited ERPs and affective attitude: Brain electrical microstate and tomography analyses. In: J.T. Cacioppo, G.G. Berntson, R. Adolphs, C.S. Carter, R.J. Davidson, M.K. McClintock, B.S. McEwen, M.J. Meaney, D.L. Schacter, E.M. Sternberg, S.S. Suomi, S.E. Taylor (Eds.), Foundations in Social Neuroscience. Cambridge: The MIT Press, pp. 599-614.

Pizzagalli, D., Koenig, T., Regard, M., Lehmann, D. (1997). Event-related potential fields and general affective style for presented face images. In: H. Witte, U. Zwiener, B. Schack and A. Doering (Eds.), Quantitative and topological EEG and MEG analysis. Jena: Druckhaus Mayer Verlag GmbH, pp. 467-470.

Pizzagalli, D., Shackman, A.J., Davidson, R.J. (2003). The functional neuroimaging of human emotion: Asymmetric contributions of cortical and subcortical circuitry. In: K. Hughdal and R.J. Davidson (Eds.), The Asymmetrical Brain. Cambridge: MIT Press, pp. 511-532. (PDF)

Pizzagalli, D.A., Treadway, M.T. (2014). Neuroimaging approaches to the study of Major Depressive Disorder: From regions to circuits. In: I.H. Gotlib, C.L. Hammen (Eds.), Handbook of Depression, 3rd Edition. New York: Guilford, pp. 202-219.

Pizzagalli, D.A., Whitton, A.E., Webb, C.A. (2018). Mood Disorders. In James N. Butcher, Jill M. Hooley (Eds.). APA Handbook of Psychopathology (Volume 1; Psychopathology: Understanding, Assessing, and Treating Adult Mental Disorders). American Psychological Association, pp. 403-427.

Romer, A.L.*, Bertocci, M. A.*, Phillips, M.L.**, Pizzagalli, D.A.** (in press). Neuroimaging and circuit mechanisms of depression. In D.S. Charney, E.J. Nestler, P. Sklar, & J.D., Buxbaum (Eds.), Charney & Nestler’s Neurobiology of Mental Illness. Oxford University Press. *Shared first author; **shared last author.

Rosso, I.M., Dillon, D.G., Pizzagalli, D.A., Rauch SL. (2015) Translational perspectives on anxiety disorders and the Research Domain Criteria construct of potential threat. In K.J. Ressler, D. Pine, B.O. Rothbaum (Eds.), Anxiety Disorders: Translational Perspectives on Diagnosis and Treatment. New York, Oxford University Press, pp. 17-29.

Treves, A., Pizzagalli, D. (2002). Vigilance and perception of social stimuli: Views from ethology and social neuroscience. In: M. Bekoff, C. Allen and G. Burghardt (Eds.), The Cognitive Animal: Empirical and Theoretical Perspectives on Animal Cognition. Cambridge: The MIT Press, pp. 463-469.

Webb, C.A., Pizzagalli, D.A. (2018). Sadness and depression. In: M. Lewis, J. M. Haviland-Jones, and L.F. Barrett (Eds.), The Handbook of Emotion, 4th Edition. New York: Guilford, pp. 859-870.

Whitton, A.E., Treadway, M.T., Ironside, M.L., Pizzagalli, D.A. (2019). Neurobiological reward-related abnormalities across mood disorders. In: J. Gruber (Ed.). The Oxford Handbook of Positive Emotion and Psychopathology. Oxford University Press, New York, NY, pp. 223-238.