Lab for Affective and Translational Neuroscience

Lab for Affective and Translational Neuroscience

Working to understand the functional neuroanatomy of depression

Using a multi-modal approach spanning different levels of analyses (e.g., environment, genes, brain, behavior), LATN scientists are working towards a better understanding of the causes, consequences, and pathophysiology of depression.

Novel psychological treatments for adolescent depression

Novel psychological treatments for adolescent depression

The Child and Adolescent Mood Disorders Laboratory is evaluating novel treatments based on cognitive, behavioral, and interpersonal approaches to mitigate stress and attenuate depressive symptoms among adolescents.

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The Center for Depression, Anxiety and Stress Research (CDASR) embraces a multi-disciplinary approach to improve our understanding of the psychological, environmental, and neurobiological factors associated with affective disorders.

The Center is home to many research projects, including studies that: utilize neuroimaging techniques to investigate the neurobiology of depression; implement and evaluate novel prevention and treatment programs for depressed adolescents; test the role of early adversities (e.g., maltreatment, trauma) and genetic variance in increasing the risk for depression and anxiety; explore psychological and neurobiological traits associated with resilience; and build computational models to study neural function in severe mental illnesses. Our goal is to identify promising targets for prevention and treatment.

Director's Message

Diego A Pizzagalli, Ph.D. is Director of the Center for Depression, Anxiety and Stress Research, and a Professor of Psychiatry at Harvard Medical School. Read More...

Upcoming Events

Wed May 6, 2015 at 9:30
DeMarneffe 218

Martha Tompson, Ph.D.
Associate Professor, Department of Psychology, Boston University

Family-Based Treatment for Childhood-onset Depressive Disorders:
Initial Results of a Randomized Clinical Trial


Wed May 20, 2015 at 9:30
DeMarneffe 218

Brian P. Marx, Ph.D.
Professor of Psychiatry, Boston University School of Medicine
Psychologist, National Center for PTSD, VA Boston Healthcare System

The Veterans After Discharge Longitudinal Registry: Project VALoR


Latest News


Christian Webb was recently promoted to Instructor in Psychiatry at Harvard Medical School. Congratulations to Dr. Webb!

Janice KileyJanice Kiley has been selected for the McLean Hospital’s Vision of Excellence Award. These awards are given to McLean employees who exemplify McLean's commitment to excellence and consistently show efforts to go above and beyond. I cannot  think of somebody more deserving of this award than Janice.  There will be a reception to honor Janice’s accomplishment on April 29, 1-2 pm.
Congratulations, Janice!

Four CDASR postdoctoral fellows were recently awarded 2014 McLean Fellowships: Alexis Whitton received the Andrew P. Merrill Memorial Research Fellow award; Ashlee Van't Veer received the Rappaport Mental Health Research Scholar Award;  Joanna Chango received the Adam Corneel Young Investigator Award; and Jeremy Stewart received the Pope-Hintz Endowed Fellowship Award. They will be using these awards to embark on exciting projects on important clinical questions.