Lab for Affective and Translational Neuroscience

Lab for Affective and Translational Neuroscience

Working to understand the functional neuroanatomy of depression

Using a multi-modal approach spanning different levels of analyses (e.g., environment, genes, brain, behavior), LATN scientists are working towards a better understanding of the causes, consequences, and pathophysiology of depression.

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Novel psychological treatments for adolescent depression

Novel psychological treatments for adolescent depression

The Child and Adolescent Mood Disorders Laboratory is evaluating novel treatments based on cognitive, behavioral, and interpersonal approaches to mitigate stress and attenuate depressive symptoms among adolescents.

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The Center for Depression, Anxiety and Stress Research (CDASR) embraces a multi-disciplinary approach to improve our understanding of the psychological, environmental, and neurobiological factors associated with affective disorders.

The Center is home to many research projects, including studies that: utilize neuroimaging techniques to investigate the neurobiology of depression; implement and evaluate novel prevention and treatment programs for depressed adolescents; test the role of early adversities (e.g., maltreatment, trauma) and genetic variance in increasing the risk for depression and anxiety; explore psychological and neurobiological traits associated with resilience; and build computational models to study neural function in severe mental illnesses. Our goal is to identify promising targets for prevention and treatment.

Director's Message

Diego A Pizzagalli, Ph.D. is Director of the Center for Depression, Anxiety and Stress Research, and a Professor of Psychiatry at Harvard Medical School. Read More...

Latest News

Poornima Kumar was recently promoted to Assistant Professor in Psychiatry at Harvard Medical School. Congratulations to Dr. Kumar!

Diego Pizzagalli receives a 2017 NARSAD Distinguished Investigator Award Grant for a new study probing a potential new target for antidepressant treatment. The award was announced by the Brain & Behavior Research Foundation.

Diego Pizzagalli received the 2017 Joel Elkes Research Award from the American College of Neuropsychopharmacology (ACNP). The ACNP presents this annual award in recognition of a scientist’s outstanding clinical contribution to neuropsychopharmacology. For a press release, see the McLean Hospital web site.